Predictive value of P wave terminal force in lead V1 for atrial fibrillation: A meta‐analysis

Background Several studies have explored the association between P wave terminal force in lead V1 (PTFV1) and risk of atrial fibrillation (AF) occurrence, but the results were controversial. This meta‐analysis aimed to examine whether abnormal PTFV1 could predict AF occurrence. Methods We searched P...

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Bibliographic Details
Published in:Annals of noninvasive electrocardiology 2020-07, Vol.25 (4), p.e12739-n/a
Main Authors: Huang, Zhuoshan, Zheng, Zhenda, Wu, Bingyuan, Tang, Leile, Xie, Xujing, Dong, Ruimin, Luo, Yanting, Li, Suhua, Zhu, Jieming, Liu, Jinlai
Format: Article
Language:English
Subjects:
atrial fibrillation
Cardiac arrhythmia
Cardiovascular diseases
Confidence intervals
Continuity (mathematics)
electrocardiogram
Fibrillation
Hemodialysis
Ischemia
Lead
Meta-analysis
P wave terminal force in lead V1
P waves
predictor
Review
Reviews
Subgroups
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Summary:Background Several studies have explored the association between P wave terminal force in lead V1 (PTFV1) and risk of atrial fibrillation (AF) occurrence, but the results were controversial. This meta‐analysis aimed to examine whether abnormal PTFV1 could predict AF occurrence. Methods We searched PubMed, Embase, and Cochrane Library databases for articles published before August 25, 2018. Pooled odds ratios (ORs) of AF occurrence were calculated using random‐effects models to explore the significance of PTFV1. Results A total of 12 studies examining 51,372 participants were included, with 9 studies analyzing PTFV1 as a categorical variable and 4 studies analyzing PTFV1 as a continuous variable. As a categorical variable, abnormal PTFV1 (>0.04 mm s) was significantly associated with AF occurrence with a pooled OR of 1.39 (95% confidence interval [CI] 1.08–1.79, p = .01). Subgroup analysis found that ORs of studies in hemodialysis patients (OR = 4.89, 95% CI 2.54–9.90, p 
ISSN:1082-720X
1542-474X
DOI:10.1111/anec.12739