Embryo Banking with Mild Ovarian Stimulation for IVF: An Alternative Strategy for Poor Prognosis Patients

Management of Poor Ovarian Reserve (POR) in in vitro fertilization remains a difficult challenge. The purpose of this retrospective cohort study was to compare the effectiveness of embryo banking strategy over a cohort of several mild stimulation cycles (Embryo Banking Strategy for Poor Prognosis/Em...

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Bibliographic Details
Published in:Journal of reproduction & infertility 2020-07, Vol.21 (3), p.176-182
Main Authors: Sini, Ivan, Polim, Arie A, Handayani, Nining, Pratiwi, Adinda, Thuffi, Rosalina, Yusup, Nuraeni, Boediono, Arief
Format: Article
Language:English
Subjects:
Banking
Birth rate
Chi-square test
Clinical outcomes
Cost analysis
Drug dosages
Embryos
In vitro fertilization
Miscarriage
Original
Ovaries
Patients
Pregnancy
Prognosis
Statistical analysis
Statistical tests
Stimulation
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Summary:Management of Poor Ovarian Reserve (POR) in in vitro fertilization remains a difficult challenge. The purpose of this retrospective cohort study was to compare the effectiveness of embryo banking strategy over a cohort of several mild stimulation cycles (Embryo Banking Strategy for Poor Prognosis/Embargo) to conventional full-dose antagonist protocol for IVF. Subjects identified as having poor ovarian response (POR) based on the Bologna criteria were recruited. In total, there were 113 subjects included in the analysis. Fifty-three subjects underwent embryo banking procedure (Embargo) protocol, and sixty subjects underwent the conventional full-dose antagonist protocol for IVF. The Chi-square test was used to compare the clinical pregnancy rate, miscarriage rate as well as live birth rate, while the Mann-Whitney U test was utilized to analyze the cost per clinical pregnancy between the two groups. A p
ISSN:2228-5482
2251-676X