Body composition analysis using CT and MRI: intra-individual intermodal comparison of muscle mass and myosteatosis

Computed tomography (CT) and magnetic resonance imaging (MRI) can quantify muscle mass and quality. However, it is still unclear if CT and MRI derived measurements can be used interchangeable. In this prospective study, fifty consecutive participants of a cancer screening program underwent same day...

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Bibliographic Details
Published in:Scientific reports 2020-07, Vol.10 (1), p.11765-11765, Article 11765
Main Authors: Faron, Anton, Sprinkart, Alois M., Kuetting, Daniel L. R., Feisst, Andreas, Isaak, Alexander, Endler, Christoph, Chang, Johannes, Nowak, Sebastian, Block, Wolfgang, Thomas, Daniel, Attenberger, Ulrike, Luetkens, Julian A.
Format: Article
Language:English
Subjects:
692/53
692/698/1671/1668
Adipose Tissue - diagnostic imaging
Adipose Tissue - pathology
Adiposity
Aged
Body Composition
Cancer screening
Computed tomography
Female
Humanities and Social Sciences
Humans
Magnetic Resonance Imaging
Male
Medical screening
Middle Aged
multidisciplinary
Muscle, Skeletal - anatomy & histology
Muscle, Skeletal - diagnostic imaging
Muscle, Skeletal - pathology
Muscles
Musculoskeletal system
Organ Size
Sarcopenia
Science
Science (multidisciplinary)
Skeletal muscle
Tomography, X-Ray Computed
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Summary:Computed tomography (CT) and magnetic resonance imaging (MRI) can quantify muscle mass and quality. However, it is still unclear if CT and MRI derived measurements can be used interchangeable. In this prospective study, fifty consecutive participants of a cancer screening program underwent same day low-dose chest CT and MRI. Cross-sectional areas (CSA) of the paraspinal skeletal muscles were obtained. CT and MRI muscle fat infiltration (MFI) were assessed by mean radiodensity in Hounsfield units (HU) and proton density fat fraction (MRI PDFF ), respectively. CSA and MFI were highly correlated between CT and MRI (CSA: r = 0.93, P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-68797-3