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Correlation of electroretinography components with visual function and prognosis of central retinal artery occlusion

We investigated the full-field electroretinographic (ERG) parameters with visual function and prognosis in central retinal artery occlusion (CRAO), according to its severity. 110 affected eyes of CRAO patients were enrolled and compared with fellow uninvolved eyes (N = 110) and normal control eyes (...

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Bibliographic Details
Published in:Scientific reports 2020-07, Vol.10 (1), p.12146, Article 12146
Main Authors: Kim, Hyeong Min, Park, Kyu Hyung, Woo, Se Joon
Format: Article
Language:English
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Summary:We investigated the full-field electroretinographic (ERG) parameters with visual function and prognosis in central retinal artery occlusion (CRAO), according to its severity. 110 affected eyes of CRAO patients were enrolled and compared with fellow uninvolved eyes (N = 110) and normal control eyes (N = 30). B/A ratio and photopic negative response amplitude (PhNR) resulted in statistically significant differences among the CRAO subgroups according to the severity of retinal ischemia. Amplitudes of PhNR indicating ganglion cell function showed a more marked decline in mild to severe ischemia than those of the B-wave. In terms of visual function and outcome, baseline visual acuity and visual field defects were correlated with B/A ratio only (both, P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-68957-5