Correlation of changes in serum S100β, NSE and inflammatory factor levels with MMSE and MoCA in intracranial tumor patients with cognitive impairment

Changes in serum neuron-specific enolase (NSE) level, S100β protein concentration and inflammatory factor levels and their correlations with cognitive impairment Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scores in intracranial tumor patients with cognitive impairm...

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Bibliographic Details
Published in:Oncology letters 2020-08, Vol.20 (2), p.1968-1972
Main Authors: Yu, Danfeng, Liu, Boyi, Jiang, Guoquan, Pei, Shiwen, Pan, Huan
Format: Article
Language:English
Subjects:
Alzheimer's disease
Brain cancer
Cognitive ability
Correlation analysis
Hypoxia
Ischemia
Medical prognosis
Memory
Nervous system
Oncology
Proteins
Studies
Tumor necrosis factor-TNF
Tumors
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Summary:Changes in serum neuron-specific enolase (NSE) level, S100β protein concentration and inflammatory factor levels and their correlations with cognitive impairment Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) scores in intracranial tumor patients with cognitive impairment were explored. Seventy patients diagnosed with intracranial tumor based on clinical symptoms and computed tomography (CT) images were selected and divided into non-cognitive impairment group (MoCA score ≥26 points, n=44) and cognitive impairment group (MoCA score
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2020.11751