Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop

Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan...

Full description

Saved in:
Bibliographic Details
Published in:Clinical pharmacology and therapeutics 2020-07, Vol.108 (1), p.29-39
Main Authors: Barrett, Jeffrey S., Bucci‐Rechtweg, Christina, Amy Cheung, S. Y., Gamalo‐Siebers, Margaret, Haertter, Sebastian, Karres, Janina, Marquard, Jan, Mulugeta, Yeruk, Ollivier, Cecile, Strougo, Ashley, Yanoff, Lisa, Yao, Lynne, Zeitler, Philip
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - physiopathology
Disease Progression
Education - methods
Humans
Hypoglycemic Agents - pharmacology
White Paper
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53
cites cdi_FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53
container_end_page 39
container_issue 1
container_start_page 29
container_title Clinical pharmacology and therapeutics
container_volume 108
creator Barrett, Jeffrey S.
Bucci‐Rechtweg, Christina
Amy Cheung, S. Y.
Gamalo‐Siebers, Margaret
Haertter, Sebastian
Karres, Janina
Marquard, Jan
Mulugeta, Yeruk
Ollivier, Cecile
Strougo, Ashley
Yanoff, Lisa
Yao, Lynne
Zeitler, Philip
description Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan for T2D addressing the viability of extrapolation. The workshop was held at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) in Orlando, Florida on March 21, 2018.
doi_str_mv 10.1002/cpt.1805
format article
fullrecord <record><control><sourceid>wiley_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7383960</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CPT1805</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53</originalsourceid><addsrcrecordid>eNp1kE1PwzAMhiMEYuND4hegHLl0OM3SDw5IaGwwaYgdhjhGaeKyQNdUTQfs39NtMMGBk2X58WPrJeSMQY8BhJe6anosAbFHukzwMIgEF_ukCwBpkIY86pAj71_btp8mySHp8BBYDH3eJQ9TNFY1tdV0-NnUqnKFaqwrqS3pbFUhDemtVRk26K_oaNksa6TjRVVYvcE8dTlV9NnVb37uqhNykKvC4-l3PSZPo-FscB9MHu_Gg5tJoHkci8CA0SGiTkwKmWAcGTcpR84wzxmkSYQszwwIrTALMU64xqSvUp0pAA1G8GNyvfVWy2yBRmPZvl7IqrYLVa-kU1b-nZR2Ll_cu4x5wtMIWsHFVqBr532N-W6XgVxHKttI5TrSFj3_fWsH_mTYAsEW-LAFrv4VycF0thF-AZR-gik</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop</title><source>Wiley</source><creator>Barrett, Jeffrey S. ; Bucci‐Rechtweg, Christina ; Amy Cheung, S. Y. ; Gamalo‐Siebers, Margaret ; Haertter, Sebastian ; Karres, Janina ; Marquard, Jan ; Mulugeta, Yeruk ; Ollivier, Cecile ; Strougo, Ashley ; Yanoff, Lisa ; Yao, Lynne ; Zeitler, Philip</creator><creatorcontrib>Barrett, Jeffrey S. ; Bucci‐Rechtweg, Christina ; Amy Cheung, S. Y. ; Gamalo‐Siebers, Margaret ; Haertter, Sebastian ; Karres, Janina ; Marquard, Jan ; Mulugeta, Yeruk ; Ollivier, Cecile ; Strougo, Ashley ; Yanoff, Lisa ; Yao, Lynne ; Zeitler, Philip</creatorcontrib><description>Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan for T2D addressing the viability of extrapolation. The workshop was held at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) in Orlando, Florida on March 21, 2018.</description><identifier>ISSN: 0009-9236</identifier><identifier>EISSN: 1532-6535</identifier><identifier>DOI: 10.1002/cpt.1805</identifier><identifier>PMID: 32017043</identifier><language>eng</language><publisher>United States: John Wiley and Sons Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Diabetes Mellitus, Type 2 - drug therapy ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - physiopathology ; Disease Progression ; Education - methods ; Humans ; Hypoglycemic Agents - pharmacology ; White Paper</subject><ispartof>Clinical pharmacology and therapeutics, 2020-07, Vol.108 (1), p.29-39</ispartof><rights>2020 The Authors. published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.</rights><rights>2020 The Authors. Clinical Pharmacology &amp; Therapeutics published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53</citedby><cites>FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32017043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barrett, Jeffrey S.</creatorcontrib><creatorcontrib>Bucci‐Rechtweg, Christina</creatorcontrib><creatorcontrib>Amy Cheung, S. Y.</creatorcontrib><creatorcontrib>Gamalo‐Siebers, Margaret</creatorcontrib><creatorcontrib>Haertter, Sebastian</creatorcontrib><creatorcontrib>Karres, Janina</creatorcontrib><creatorcontrib>Marquard, Jan</creatorcontrib><creatorcontrib>Mulugeta, Yeruk</creatorcontrib><creatorcontrib>Ollivier, Cecile</creatorcontrib><creatorcontrib>Strougo, Ashley</creatorcontrib><creatorcontrib>Yanoff, Lisa</creatorcontrib><creatorcontrib>Yao, Lynne</creatorcontrib><creatorcontrib>Zeitler, Philip</creatorcontrib><title>Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop</title><title>Clinical pharmacology and therapeutics</title><addtitle>Clin Pharmacol Ther</addtitle><description>Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan for T2D addressing the viability of extrapolation. The workshop was held at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) in Orlando, Florida on March 21, 2018.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - physiopathology</subject><subject>Disease Progression</subject><subject>Education - methods</subject><subject>Humans</subject><subject>Hypoglycemic Agents - pharmacology</subject><subject>White Paper</subject><issn>0009-9236</issn><issn>1532-6535</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><recordid>eNp1kE1PwzAMhiMEYuND4hegHLl0OM3SDw5IaGwwaYgdhjhGaeKyQNdUTQfs39NtMMGBk2X58WPrJeSMQY8BhJe6anosAbFHukzwMIgEF_ukCwBpkIY86pAj71_btp8mySHp8BBYDH3eJQ9TNFY1tdV0-NnUqnKFaqwrqS3pbFUhDemtVRk26K_oaNksa6TjRVVYvcE8dTlV9NnVb37uqhNykKvC4-l3PSZPo-FscB9MHu_Gg5tJoHkci8CA0SGiTkwKmWAcGTcpR84wzxmkSYQszwwIrTALMU64xqSvUp0pAA1G8GNyvfVWy2yBRmPZvl7IqrYLVa-kU1b-nZR2Ll_cu4x5wtMIWsHFVqBr532N-W6XgVxHKttI5TrSFj3_fWsH_mTYAsEW-LAFrv4VycF0thF-AZR-gik</recordid><startdate>202007</startdate><enddate>202007</enddate><creator>Barrett, Jeffrey S.</creator><creator>Bucci‐Rechtweg, Christina</creator><creator>Amy Cheung, S. Y.</creator><creator>Gamalo‐Siebers, Margaret</creator><creator>Haertter, Sebastian</creator><creator>Karres, Janina</creator><creator>Marquard, Jan</creator><creator>Mulugeta, Yeruk</creator><creator>Ollivier, Cecile</creator><creator>Strougo, Ashley</creator><creator>Yanoff, Lisa</creator><creator>Yao, Lynne</creator><creator>Zeitler, Philip</creator><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>202007</creationdate><title>Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop</title><author>Barrett, Jeffrey S. ; Bucci‐Rechtweg, Christina ; Amy Cheung, S. Y. ; Gamalo‐Siebers, Margaret ; Haertter, Sebastian ; Karres, Janina ; Marquard, Jan ; Mulugeta, Yeruk ; Ollivier, Cecile ; Strougo, Ashley ; Yanoff, Lisa ; Yao, Lynne ; Zeitler, Philip</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Diabetes Mellitus, Type 2 - drug therapy</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - physiopathology</topic><topic>Disease Progression</topic><topic>Education - methods</topic><topic>Humans</topic><topic>Hypoglycemic Agents - pharmacology</topic><topic>White Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barrett, Jeffrey S.</creatorcontrib><creatorcontrib>Bucci‐Rechtweg, Christina</creatorcontrib><creatorcontrib>Amy Cheung, S. Y.</creatorcontrib><creatorcontrib>Gamalo‐Siebers, Margaret</creatorcontrib><creatorcontrib>Haertter, Sebastian</creatorcontrib><creatorcontrib>Karres, Janina</creatorcontrib><creatorcontrib>Marquard, Jan</creatorcontrib><creatorcontrib>Mulugeta, Yeruk</creatorcontrib><creatorcontrib>Ollivier, Cecile</creatorcontrib><creatorcontrib>Strougo, Ashley</creatorcontrib><creatorcontrib>Yanoff, Lisa</creatorcontrib><creatorcontrib>Yao, Lynne</creatorcontrib><creatorcontrib>Zeitler, Philip</creatorcontrib><collection>Wiley_OA刊</collection><collection>Wiley-Blackwell Free Backfiles(OpenAccess)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical pharmacology and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barrett, Jeffrey S.</au><au>Bucci‐Rechtweg, Christina</au><au>Amy Cheung, S. Y.</au><au>Gamalo‐Siebers, Margaret</au><au>Haertter, Sebastian</au><au>Karres, Janina</au><au>Marquard, Jan</au><au>Mulugeta, Yeruk</au><au>Ollivier, Cecile</au><au>Strougo, Ashley</au><au>Yanoff, Lisa</au><au>Yao, Lynne</au><au>Zeitler, Philip</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop</atitle><jtitle>Clinical pharmacology and therapeutics</jtitle><addtitle>Clin Pharmacol Ther</addtitle><date>2020-07</date><risdate>2020</risdate><volume>108</volume><issue>1</issue><spage>29</spage><epage>39</epage><pages>29-39</pages><issn>0009-9236</issn><eissn>1532-6535</eissn><abstract>Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan for T2D addressing the viability of extrapolation. The workshop was held at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) in Orlando, Florida on March 21, 2018.</abstract><cop>United States</cop><pub>John Wiley and Sons Inc</pub><pmid>32017043</pmid><doi>10.1002/cpt.1805</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0009-9236
ispartof Clinical pharmacology and therapeutics, 2020-07, Vol.108 (1), p.29-39
issn 0009-9236
1532-6535
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7383960
source Wiley
subjects Adolescent
Adult
Age Factors
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - physiopathology
Disease Progression
Education - methods
Humans
Hypoglycemic Agents - pharmacology
White Paper
title Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T13%3A02%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pediatric%20Extrapolation%20in%20Type%202%20Diabetes:%20Future%20Implications%20of%20a%20Workshop&rft.jtitle=Clinical%20pharmacology%20and%20therapeutics&rft.au=Barrett,%20Jeffrey%20S.&rft.date=2020-07&rft.volume=108&rft.issue=1&rft.spage=29&rft.epage=39&rft.pages=29-39&rft.issn=0009-9236&rft.eissn=1532-6535&rft_id=info:doi/10.1002/cpt.1805&rft_dat=%3Cwiley_pubme%3ECPT1805%3C/wiley_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3775-d0dc2eec8d90b513e13d93e31eff10986e1fbd05caeb2e783ce84a9cba00c0d53%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/32017043&rfr_iscdi=true