Pediatric Case of Severe COVID-19 With Shock and Multisystem Inflammation

While the majority of pediatric coronavirus disease 2019 (COVID-19) cases have not been critical, occurrences of a multisystem inflammatory syndrome in children (MIS-C) have been emerging as the pandemic progresses. Herein, we report our experience with a pediatric COVID-19 case that presented with...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2020-06, Vol.12 (6)
Main Authors: Nguyen, David C, Haydar, Hanan, Pace, Elizabeth R, Zhang, Xiaochun Susan, Dobbs, Katherine R
Format: Article
Language:English
Subjects:
Infectious Disease
Pediatrics
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Summary:While the majority of pediatric coronavirus disease 2019 (COVID-19) cases have not been critical, occurrences of a multisystem inflammatory syndrome in children (MIS-C) have been emerging as the pandemic progresses. Herein, we report our experience with a pediatric COVID-19 case that presented with shock and multisystem inflammation. Our patient notably had multiple negative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reverse transcription polymerase chain reaction (RT-PCR) assays but tested positive for SARS-CoV-2 IgG antibody. This case not only highlights the utility of SARS-CoV-2 IgG in the diagnosis of COVID-19 when RT-PCR is negative but suggests MIS-C may be a post-infectious immune-mediated process.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.8915