Best period to replace or change plastic stents with self-expandable metallic stents using multivariate competing risk regression analysis

In endoscopic biliary drainage (EBD) for various benign and malignant biliary disorders, the appropriate timing to replace or change a plastic stent (PS) with a self-expandable metallic stent (SEMS) remains unclear. This study aimed to define the best period to replace or change a PS with a SEMS. Be...

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Bibliographic Details
Published in:Scientific reports 2020-08, Vol.10 (1), p.13080-13080, Article 13080
Main Authors: Chiba, Masafumi, Kato, Masayuki, Kinoshita, Yuji, Shimamoto, Nana, Tomita, Youichi, Abe, Takahiro, Kawahara, Yosuke, Koyama, Seita, Kanazawa, Keisuke, Takakura, Kazuki, Tsukinaga, Shintaro, Nakano, Masanori, Torisu, Yuichi, Toyoizumi, Hirobumi, Ikeda, Keiichi, Arakawa, Hiroshi, Sumiyama, Kazuki
Format: Article
Language:English
Subjects:
692/4020/1503
692/699/1503/1328
692/699/1503/1712
Adult
Aged
Aged, 80 and over
Benign
Bile ducts
Biliary Tract Neoplasms - surgery
Cancer
Feasibility Studies
Female
Humanities and Social Sciences
Humans
Implants
Male
Middle Aged
multidisciplinary
Multivariate Analysis
Pancreatic cancer
Plastics
Recurrence
Regression Analysis
Retrospective Studies
Risk analysis
Risk Assessment
Science
Science (multidisciplinary)
Self Expandable Metallic Stents
Stents
Young Adult
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Summary:In endoscopic biliary drainage (EBD) for various benign and malignant biliary disorders, the appropriate timing to replace or change a plastic stent (PS) with a self-expandable metallic stent (SEMS) remains unclear. This study aimed to define the best period to replace or change a PS with a SEMS. Between January 1, 2012, and December 31, 2018, 1,887 consecutive EBD procedures, including 170 SEMS placements, were retrospectively identified. The period to recurrent biliary obstruction (PRBO) was estimated and compared between the malignant and benign groups and according to each disease using time to event analysis and competing risk analysis. Compared with the benign group, the malignant group had significantly shorter median PRBO with interquartile range (IQR) after PS placement [108 (39 – 270) vs. 613 (191 – 1,329) days, P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-70081-3