Empathy and theory of mind in multiple sclerosis: A protocol for systematic review and meta-analysis

Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS). Recently, numerous studies have shown that MS disrupts a number of social cognitive abilities, including empathy, theory of mind (ToM), and facial emotion recognition. In contrast to well-documen...

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Bibliographic Details
Published in:Medicine (Baltimore) 2020-08, Vol.99 (33), p.e21773-e21773
Main Authors: Lin, XiaoGuang, Zhang, XueLing, Liu, QinQin, Zhao, PanWen, Zhong, JianGuo, Pan, PingLei, Wang, GenDi, Yi, ZhongQuan
Format: Article
Language:English
Subjects:
Empathy
Humans
Meta-Analysis as Topic
Multiple Sclerosis - psychology
Study Protocol Systematic Review
Systematic Reviews as Topic
Theory of Mind
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Summary:Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system (CNS). Recently, numerous studies have shown that MS disrupts a number of social cognitive abilities, including empathy, theory of mind (ToM), and facial emotion recognition. In contrast to well-documented deficits in the core social cognitive domains of ToM and facial emotion recognition, it is not clear the broad and specific subcomponents of empathy processing affected. In addition, the specific subcomponents of ToM affected in MS are also unclear. The aim of this study is to conduct a systematic review and meta-analysis to characterize the performance of empathy and ToM in MS. A systematic literature search will be performed for eligible studies published up to July 1st, 2020 in 3 international databases (PubMed, Web of Science, and Embase). The work such as article retrieval, screen, quality evaluation, data collection will be conducted by 2 independent researchers. Meta-analysis will be performed using Stata 15.0 software. The results of this study will be published in a peer-reviewed journal. This meta-analysis will provide a high-quality synthesis from existing evidence for the performance of empathy and ToM in MS. INPLASY202070029.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000021773