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Full recovery of near complete tear of anterior cruciate ligament without surgery: a case report
The anterior cruciate ligament (ACL) is the region where spraining or tearing is most prevalent when the knee is injured. Complete ACL ruptures have a much less favorable outcome without surgical intervention. Polydeoxyribonucleotide (PDRN) is a relatively safe substance widely used for regenerative...
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| Published in: | Medicine (Baltimore) 2020-05, Vol.99 (18), p.e19899-e19899 |
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| Main Authors: | , , , , , , , |
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| cites | cdi_FETCH-LOGICAL-c4508-ac073d9c0331e3c803779f5a5db1efa042de42e8e5aabf9189f62320d2b817963 |
| container_end_page | e19899 |
| container_issue | 18 |
| container_start_page | e19899 |
| container_title | Medicine (Baltimore) |
| container_volume | 99 |
| creator | Kim, Yoo Na Baek, Jungwon Kim, Young Hoon Hwang, Jaewoong Ko, Yu Ri Lee, Min soo Kim, Young chan Park, Hue Jung |
| description | The anterior cruciate ligament (ACL) is the region where spraining or tearing is most prevalent when the knee is injured. Complete ACL ruptures have a much less favorable outcome without surgical intervention. Polydeoxyribonucleotide (PDRN) is a relatively safe substance widely used for regenerative therapy.
A 43-year-old female patient visited our clinic with Rt. knee pain after slipping, which she rated as 7/10 on a numeric rating scale.
She was diagnosed as having a near complete tear of the ACL at the femoral attachment, partial tear of the lateral collateral ligament.
Ultrasound-guided PDRN injections were carried out 5 times at intervals of about 2 weeks.
At 3-month follow-up, the patient demonstrated an improvement in knee symptoms (numeric rating scale 0) and ROM without any complications. Even after 2 years and 5 months since the diagnosis, she has been doing her daily life well without any pain.
This is the first report of successful PDRN injection for near complete tear of ACL and partial tear of lateral collateral ligament without surgery. |
| doi_str_mv | 10.1097/MD.0000000000019899 |
| format | article |
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A 43-year-old female patient visited our clinic with Rt. knee pain after slipping, which she rated as 7/10 on a numeric rating scale.
She was diagnosed as having a near complete tear of the ACL at the femoral attachment, partial tear of the lateral collateral ligament.
Ultrasound-guided PDRN injections were carried out 5 times at intervals of about 2 weeks.
At 3-month follow-up, the patient demonstrated an improvement in knee symptoms (numeric rating scale 0) and ROM without any complications. Even after 2 years and 5 months since the diagnosis, she has been doing her daily life well without any pain.
This is the first report of successful PDRN injection for near complete tear of ACL and partial tear of lateral collateral ligament without surgery.</description><identifier>ISSN: 0025-7974</identifier><identifier>EISSN: 1536-5964</identifier><identifier>DOI: 10.1097/MD.0000000000019899</identifier><identifier>PMID: 32358356</identifier><language>eng</language><publisher>United States: the Author(s). Published by Wolters Kluwer Health, Inc</publisher><subject>Adult ; Anterior Cruciate Ligament Injuries - therapy ; Clinical Case Report ; Female ; Humans ; Injections, Intra-Articular ; Polydeoxyribonucleotides - administration & dosage ; Recovery of Function ; Regenerative Medicine - methods ; Rupture, Spontaneous - therapy ; Treatment Outcome ; Wound Healing</subject><ispartof>Medicine (Baltimore), 2020-05, Vol.99 (18), p.e19899-e19899</ispartof><rights>the Author(s). Published by Wolters Kluwer Health, Inc.</rights><rights>Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4508-ac073d9c0331e3c803779f5a5db1efa042de42e8e5aabf9189f62320d2b817963</citedby><cites>FETCH-LOGICAL-c4508-ac073d9c0331e3c803779f5a5db1efa042de42e8e5aabf9189f62320d2b817963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440291/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7440291/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32358356$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Yoo Na</creatorcontrib><creatorcontrib>Baek, Jungwon</creatorcontrib><creatorcontrib>Kim, Young Hoon</creatorcontrib><creatorcontrib>Hwang, Jaewoong</creatorcontrib><creatorcontrib>Ko, Yu Ri</creatorcontrib><creatorcontrib>Lee, Min soo</creatorcontrib><creatorcontrib>Kim, Young chan</creatorcontrib><creatorcontrib>Park, Hue Jung</creatorcontrib><title>Full recovery of near complete tear of anterior cruciate ligament without surgery: a case report</title><title>Medicine (Baltimore)</title><addtitle>Medicine (Baltimore)</addtitle><description>The anterior cruciate ligament (ACL) is the region where spraining or tearing is most prevalent when the knee is injured. Complete ACL ruptures have a much less favorable outcome without surgical intervention. Polydeoxyribonucleotide (PDRN) is a relatively safe substance widely used for regenerative therapy.
A 43-year-old female patient visited our clinic with Rt. knee pain after slipping, which she rated as 7/10 on a numeric rating scale.
She was diagnosed as having a near complete tear of the ACL at the femoral attachment, partial tear of the lateral collateral ligament.
Ultrasound-guided PDRN injections were carried out 5 times at intervals of about 2 weeks.
At 3-month follow-up, the patient demonstrated an improvement in knee symptoms (numeric rating scale 0) and ROM without any complications. Even after 2 years and 5 months since the diagnosis, she has been doing her daily life well without any pain.
This is the first report of successful PDRN injection for near complete tear of ACL and partial tear of lateral collateral ligament without surgery.</description><subject>Adult</subject><subject>Anterior Cruciate Ligament Injuries - therapy</subject><subject>Clinical Case Report</subject><subject>Female</subject><subject>Humans</subject><subject>Injections, Intra-Articular</subject><subject>Polydeoxyribonucleotides - administration & dosage</subject><subject>Recovery of Function</subject><subject>Regenerative Medicine - methods</subject><subject>Rupture, Spontaneous - therapy</subject><subject>Treatment Outcome</subject><subject>Wound Healing</subject><issn>0025-7974</issn><issn>1536-5964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpdkUtv1DAUhS0EokPhFyAhL9mk-BnHLJBQSwGpFRtYmzvOzUzAiQfb6aj_Hg9TysMb-_qc-_nKh5DnnJ1xZs2r64sz9mdx21n7gKy4lm2jbasekhVjQjfGGnVCnuT8rZqkEeoxOZFC6k7qdkW-Xi4h0IQ-3mC6pXGgM0KiPk67gAVpOVT1FuaCaYxVSYsfoSph3MCEc6H7sWzjUmhe0qYyXlOgHjJW6C6m8pQ8GiBkfHa3n5Ivl-8-n39orj69_3j-9qrxSrOuAc-M7K1nUnKUvmPSGDto0P2a4wBMiR6VwA41wHqwvLNDK6RgvVh33NhWnpI3R-5uWU_Y-zpZguB2aZwg3boIo_tXmcet28QbZ5RiwvIKeHkHSPHHgrm4acweQ4AZ45KdkNa0rdatqlZ5tPoUc0443D_DmTtk464v3P_Z1K4Xf0943_M7jGpQR8M-hvrb-XtY9pjcFiGU7S-eNlY0gol6Ypw1B3QnfwJvpJtQ</recordid><startdate>20200501</startdate><enddate>20200501</enddate><creator>Kim, Yoo Na</creator><creator>Baek, Jungwon</creator><creator>Kim, Young Hoon</creator><creator>Hwang, Jaewoong</creator><creator>Ko, Yu Ri</creator><creator>Lee, Min soo</creator><creator>Kim, Young chan</creator><creator>Park, Hue Jung</creator><general>the Author(s). Published by Wolters Kluwer Health, Inc</general><general>Wolters Kluwer Health</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20200501</creationdate><title>Full recovery of near complete tear of anterior cruciate ligament without surgery: a case report</title><author>Kim, Yoo Na ; Baek, Jungwon ; Kim, Young Hoon ; Hwang, Jaewoong ; Ko, Yu Ri ; Lee, Min soo ; Kim, Young chan ; Park, Hue Jung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4508-ac073d9c0331e3c803779f5a5db1efa042de42e8e5aabf9189f62320d2b817963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult</topic><topic>Anterior Cruciate Ligament Injuries - therapy</topic><topic>Clinical Case Report</topic><topic>Female</topic><topic>Humans</topic><topic>Injections, Intra-Articular</topic><topic>Polydeoxyribonucleotides - administration & dosage</topic><topic>Recovery of Function</topic><topic>Regenerative Medicine - methods</topic><topic>Rupture, Spontaneous - therapy</topic><topic>Treatment Outcome</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Yoo Na</creatorcontrib><creatorcontrib>Baek, Jungwon</creatorcontrib><creatorcontrib>Kim, Young Hoon</creatorcontrib><creatorcontrib>Hwang, Jaewoong</creatorcontrib><creatorcontrib>Ko, Yu Ri</creatorcontrib><creatorcontrib>Lee, Min soo</creatorcontrib><creatorcontrib>Kim, Young chan</creatorcontrib><creatorcontrib>Park, Hue Jung</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Medicine (Baltimore)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Yoo Na</au><au>Baek, Jungwon</au><au>Kim, Young Hoon</au><au>Hwang, Jaewoong</au><au>Ko, Yu Ri</au><au>Lee, Min soo</au><au>Kim, Young chan</au><au>Park, Hue Jung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Full recovery of near complete tear of anterior cruciate ligament without surgery: a case report</atitle><jtitle>Medicine (Baltimore)</jtitle><addtitle>Medicine (Baltimore)</addtitle><date>2020-05-01</date><risdate>2020</risdate><volume>99</volume><issue>18</issue><spage>e19899</spage><epage>e19899</epage><pages>e19899-e19899</pages><issn>0025-7974</issn><eissn>1536-5964</eissn><abstract>The anterior cruciate ligament (ACL) is the region where spraining or tearing is most prevalent when the knee is injured. Complete ACL ruptures have a much less favorable outcome without surgical intervention. Polydeoxyribonucleotide (PDRN) is a relatively safe substance widely used for regenerative therapy.
A 43-year-old female patient visited our clinic with Rt. knee pain after slipping, which she rated as 7/10 on a numeric rating scale.
She was diagnosed as having a near complete tear of the ACL at the femoral attachment, partial tear of the lateral collateral ligament.
Ultrasound-guided PDRN injections were carried out 5 times at intervals of about 2 weeks.
At 3-month follow-up, the patient demonstrated an improvement in knee symptoms (numeric rating scale 0) and ROM without any complications. Even after 2 years and 5 months since the diagnosis, she has been doing her daily life well without any pain.
This is the first report of successful PDRN injection for near complete tear of ACL and partial tear of lateral collateral ligament without surgery.</abstract><cop>United States</cop><pub>the Author(s). Published by Wolters Kluwer Health, Inc</pub><pmid>32358356</pmid><doi>10.1097/MD.0000000000019899</doi><oa>free_for_read</oa></addata></record> |
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| issn | 0025-7974 1536-5964 |
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| source | HEAL-Link subscriptions: Lippincott Williams & Wilkins; IngentaConnect Journals; PubMed Central |
| subjects | Adult Anterior Cruciate Ligament Injuries - therapy Clinical Case Report Female Humans Injections, Intra-Articular Polydeoxyribonucleotides - administration & dosage Recovery of Function Regenerative Medicine - methods Rupture, Spontaneous - therapy Treatment Outcome Wound Healing |
| title | Full recovery of near complete tear of anterior cruciate ligament without surgery: a case report |
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