Dynamic activity patterns in the anterior temporal lobe represents object semantics

The anterior temporal lobe (ATL) is considered a crucial area for the representation of transmodal concepts. Recent evidence suggests that specific regions within the ATL support the representation of individual object concepts, as shown by studies combining multivariate analysis methods and explici...

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Bibliographic Details
Published in:Cognitive neuroscience 2020-07, Vol.11 (3), p.111-121
Main Author: Clarke, Alex
Format: Article
Language:English
Subjects:
Activity patterns
Adolescent
Adult
ATL
Concept Formation - physiology
Cortex (perirhinal)
Cortex (temporal)
Drug Resistant Epilepsy - physiopathology
Electrocorticography
Female
Functional magnetic resonance imaging
Humans
Male
Multivariate analysis
Pattern Recognition, Visual - physiology
perirhinal
Perirhinal Cortex - physiology
RSA
Semantics
Temporal lobe
Temporal Lobe - physiology
Theta rhythms
time course
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Summary:The anterior temporal lobe (ATL) is considered a crucial area for the representation of transmodal concepts. Recent evidence suggests that specific regions within the ATL support the representation of individual object concepts, as shown by studies combining multivariate analysis methods and explicit measures of semantic knowledge. This research looks to further our understanding by probing conceptual representations at a spatially and temporally resolved neural scale. Representational similarity analysis was applied to human intracranial recordings from anatomically defined lateral to medial ATL sub-regions. Neural similarity patterns were tested against semantic similarity measures, where semantic similarity was defined by a hybrid corpus-based and feature-based approach. Analyses show that the perirhinal cortex, in the medial ATL, significantly related to semantic effects around 200 to 400 ms, and were greater than more lateral ATL regions. Further, semantic effects were present in low frequency (theta and alpha) oscillatory phase signals. These results provide converging support that more medial regions of the ATL support the representation of basic-level visual object concepts within the first 400 ms, and provide a bridge between prior fMRI and MEG work by offering detailed evidence for the presence of conceptual representations within the ATL.
ISSN:1758-8928
1758-8936
DOI:10.1080/17588928.2020.1742678