WHODrug: A Global, Validated and Updated Dictionary for Medicinal Information

The WHODrug medicinal information dictionary is a worldwide source of global medicinal information with the aim to facilitate the coding of medications in clinical trials as well as identification of medication-related problems when monitoring patient safety, thereby supporting the development and u...

Full description

Saved in:
Bibliographic Details
Published in:Therapeutic innovation & regulatory science 2020-09, Vol.54 (5), p.1116-1122
Main Authors: Lagerlund, Olof, Strese, Sara, Fladvad, Malin, Lindquist, Marie
Format: Article
Language:English
Subjects:
Clinical trials
Data exchange
Data structures
Dictionaries
Drug Safety and Pharmacovigilance
Educational Review
Marketing
Medicine
Patient safety
Pharmaceutical industry
Pharmaceuticals
Pharmacotherapy
Pharmacy
Safety
Side effects
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The WHODrug medicinal information dictionary is a worldwide source of global medicinal information with the aim to facilitate the coding of medications in clinical trials as well as identification of medication-related problems when monitoring patient safety, thereby supporting the development and usage of effective and safe medications. WHODrug contains individual trade names, active ingredients and additional information such as marketing authorisation holder, country of sale, pharmaceutical form and strength. All related medications are linked using a structured WHODrug alphanumeric code, connecting trade names and variation of the ingredient with the active moiety of the ingredient. Medications in WHODrug are classified using the ATC system and clustered into Standardised Drug Groupings, to allow for grouping of medications with one or more properties in common. The built-in data structure and the classification of medications in WHODrug facilitate various ways of aggregating medications for identification and analysis of possible adverse drug reactions. The different information levels in WHODrug are used to explore the relationship between a medication or a class of medications and an adverse event. By using WHODrug in clinical trials and post-marketing safety, accurate and standardised medication information can be achieved globally and allow easy information exchange. To meet the demands of WHODrug users from the pharmaceutical industry, academia and regulatory authorities, it is relevant to keep the dictionary comprehensive, validated and constantly updated on a global scale.
ISSN:2168-4790
2168-4804
DOI:10.1007/s43441-020-00130-6