Headache and pleocytosis in CSF associated with COVID-19: case report

In December 2019, a new coronavirus infection was identified in China. Although the clinical presentation of COVID-19 is predominantly respiratory, more than 35%% of patients have neurological symptoms. We report an elderly female with asthenia, dry cough, anosmia, ageusia, fever, nausea, and a seve...

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Bibliographic Details
Published in:Neurological sciences 2020-11, Vol.41 (11), p.3021-3022
Main Authors: de Oliveira, Felipe Araújo Andrade, Palmeira, Danylo César Correia, Rocha-Filho, Pedro Augusto Sampaio
Format: Article
Language:English
Subjects:
Aged
Betacoronavirus
Coronavirus Infections - cerebrospinal fluid
Coronavirus Infections - complications
COVID-19
Female
Headache - etiology
Humans
Leukocytosis - cerebrospinal fluid
Medicine
Medicine & Public Health
Meningitis, Viral - virology
Neurology
Neuroradiology
Neurosurgery
Pandemics
Pneumonia, Viral - cerebrospinal fluid
Pneumonia, Viral - complications
Psychiatry
SARS-CoV-2
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Summary:In December 2019, a new coronavirus infection was identified in China. Although the clinical presentation of COVID-19 is predominantly respiratory, more than 35%% of patients have neurological symptoms. We report an elderly female with asthenia, dry cough, anosmia, ageusia, fever, nausea, and a severe and persistent headache. She had confirmed COVID-19 using the nasal swab RT-PCR technique. Her cranial tomography was normal. The CSF analysis demonstrated a cell count of 21 cells/mm 3 (80% lymphocytes and 20% monocytes), 34 mg/dl protein, and 79 mg/dl glucose. She improved after 4 days. Our report draws attention to the meningeal involvement of SARS-Cov-2.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-020-04694-x