Service Evaluation of Methoxyflurane Versus Standard Care for Overall Management of Patients with Pain Due to Injury

• Published in: Advances in therapy 2020-05, Vol.37 (5), p.2520-2527
• Main Authors: Young, Louise, Bailey, George P., McKinlay, Jayne A. C.
• Format: Article
• Language: English
• Subjects: Acute Pain - drug therapy; Acute Pain - etiology; Adult; Anesthetics, Inhalation - administration & dosage; Anesthetics, Inhalation - adverse effects; Anesthetics, Inhalation - therapeutic use; Brief Report; Cardiology; Emergency Service, Hospital - statistics & numerical data; Endocrinology; Female; Glasgow Coma Scale; Humans; Internal Medicine; Length of Stay - statistics & numerical data; Male; Medicine; Medicine & Public Health; Methoxyflurane - administration & dosage; Methoxyflurane - adverse effects; Methoxyflurane - therapeutic use; Middle Aged; Oncology; Pain Management; Pain Measurement; Pharmacology/Toxicology; Rheumatology; Time Factors; Trauma Centers; Wounds and Injuries - complications
• ISSN: 0741-238X; 1865-8652
• DOI: 10.1007/s12325-020-01294-1

Introduction Inhaled methoxyflurane is an analgesic used for the emergency relief of moderate to severe pain in conscious adult patients with trauma and associated pain that is increasingly being used in hospital emergency departments to provide rapid analgesia. It is widely accepted that effective pain relief can facilitate patient care and flow through the emergency department (ED). The main aim of this evaluation was to assess the impact of inhaled methoxyflurane on patient length of stay (LOS) in the ED compared with standard care. Methods Adult patients with moderate to severe trauma pain and Glasgow coma score of 15 were included in the evaluation. Evaluation forms were completed for 79 patients who received methoxyflurane and were matched with 80 patients who received standard care. Results Overall the mean time spent in the ED was reduced by 71 min in those patients who were administered methoxyflurane compared with patients who received standard care. Furthermore, analysis of LOS by injury type demonstrated a reduction in ED LOS by 183 min for patients with shoulder dislocation who were treated with methoxyflurane compared with patients who received standard care. There was no reduction in ED LOS for patients with lower limb, hip or pelvic injuries between the two treatment groups. Conclusion Use of methoxyflurane in adult patients with trauma pain significantly reduced the ED LOS and may potentially improve patient flow through the ED.