Celiac Dietary Adherence Test and Standardized Dietician Evaluation in Assessment of Adherence to a Gluten-Free Diet in Patients with Celiac Disease

• Published in: Nutrients 2020-07, Vol.12 (8), p.2300
• Main Authors: Gładyś, Katarzyna, Dardzińska, Jolanta, Guzek, Marek, Adrych, Krystian, Małgorzewicz, Sylwia
• Format: Article
• Language: English
• Subjects: Additives; Adolescent; Adult; Adults; Aged; Antibodies; Autoantibodies - blood; Autoantibodies - immunology; Autoimmune diseases; Bioethics; Biopsy; Celiac disease; Celiac Disease - blood; Celiac Disease - diet therapy; Celiac Disease - pathology; Clinical medicine; Correlation analysis; Diet; Diet Surveys - methods; Diet Surveys - standards; Diet Surveys - statistics & numerical data; Diet, Gluten-Free - statistics & numerical data; Dietitians; Disease; Duodenum - pathology; Evaluation; Female; Food; Food additives; Gastroenterology; Gliadin; Gliadin - immunology; Gluten; GTP-Binding Proteins - immunology; Humans; Likert scale; Male; Medical treatment; Methods; Middle Aged; Patient Compliance - statistics & numerical data; Patients; Questionnaires; Reproducibility of Results; Serology; Transglutaminase 2; Transglutaminases - immunology; Womens health; Young Adult
• ISSN: 2072-6643; 2072-6643
• DOI: 10.3390/nu12082300

Adherence to a gluten-free diet (GFD) is currently the mainstay of treatment strategy for celiac disease (CD). The aim of our study was measuring a GFD adherence in CD patients using two newly validated methods of dietary assessment-Standardized Dietician Evaluation (SDE) and the Celiac Dietary Adherence Test (CDAT). Ninety-two adults with CD were evaluated by a registered dietitian with extensive experience with the use of SDE and CDAT. Duodenal biopsy was performed and blood was drawn for serum anti-endomysial, anti-deamidated gliadin peptide and anti-tissue transglutaminase antibodies in forty four of those patients. The results of CDAT and SDE were very convergent, but SDE scores better correlated with serologic and histologic findings. As many as 24-52% of study participants did not adhere well enough to a GFD. Insufficient adherence to a GFD in CD patients is still a significant problem. The knowledge about gluten content in food ingredients and additives is very low among adults with CD. SDE is the most accurate method in assessing compliance with a GFD and is especially helpful in determining hidden sources of gluten. The CDAT may be a fast tool for screening for a GFD adherence in CD patients.