Efficacy and safety of traditional Chinese herbal formula combined with western medicine for uterine fibroid: A protocol for systematic review and meta-analysis

Clinical studies found that the combination of traditional Chinese herbal formula, and western medicine therapy are better in shrinking fibroids and improve other symptoms. This study aims to systematically evaluate the efficacy and safety traditional Chinese herbal formula combined with western med...

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Bibliographic Details
Published in:Medicine (Baltimore) 2020-09, Vol.99 (36), p.e22039-e22039
Main Authors: Fu, Yu, Fan, Yihua, Fan, Wei, Lv, Yubing, Ai, Siyu, Yu, Chenghao
Format: Article
Language:English
Subjects:
China - epidemiology
Combined Modality Therapy
Drug Prescriptions - standards
Drugs, Chinese Herbal - therapeutic use
Female
Humans
Leiomyoma - drug therapy
Medicine, Chinese Traditional - methods
Randomized Controlled Trials as Topic
Safety
Study Protocol Systematic Review
Treatment Outcome
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Summary:Clinical studies found that the combination of traditional Chinese herbal formula, and western medicine therapy are better in shrinking fibroids and improve other symptoms. This study aims to systematically evaluate the efficacy and safety traditional Chinese herbal formula combined with western medicine in the treatment of uterine fibroids. Randomized controlled trials of traditional Chinese herbal formula combined with western medicine for uterine fibroids patients will be searched in PubMed, Medline, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Chongqing VIP Chinese Science and Technology Periodical Database, Chinese Biological and Medical database (CMB), and Wanfang database from inception to August 2020. Two researchers will perform data extraction and risk of bias assessment independently. Statistical analysis will be conducted in RevMan 5.3. This study will summarize the present evidence by exploring the efficacy and safety of traditional Chinese herbal formula combined with western medicine in the treatment of uterine fibroids CONCLUSIONS:: The findings of the study will help to determine potential benefits of traditional Chinese herbal formula combined with western medicine in the treatment of uterine fibroids. The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. DOI 10.17605/OSF.IO/XUA8V.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000022039