Treatment of isolated mediastinal and hilar recurrence of lung cancer with bronchoscopic endobronchial ultrasound guided intratumoral injection of chemotherapy with cisplatin

Highlights • Treatment options for isolated mediastinal lung cancer recurrence are limited. • EBUS guided intratumoral Cisplatin represents a novel therapeutic option. • 70% of treated patients achieved complete or partial remission in our series. • Patients who responded to therapy had higher overa...

Full description

Saved in:
Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2015-12, Vol.90 (3), p.542-547
Main Authors: Mehta, Hiren J, Begnaud, Abbie, Penley, Andrea M, Wynne, John, Malhotra, Paras, Fernandez-Bussy, Sebastian, Cope, Jessica M, Shuster, Jonathan J, Jantz, Michael A
Format: Article
Language:English
Subjects:
Aged
Antineoplastic Agents - administration & dosage
Cisplatin - administration & dosage
endobronchial ultrasound
Female
Hematology, Oncology and Palliative Medicine
Humans
Injections, Intralesional - methods
Kaplan-Meier Estimate
Lung cancer recurrence
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - drug therapy
Lung Neoplasms - mortality
Lung Neoplasms - pathology
Male
Mediastinal Neoplasms - diagnostic imaging
Mediastinal Neoplasms - drug therapy
Mediastinal Neoplasms - mortality
Mediastinal Neoplasms - pathology
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Staging
Pulmonary/Respiratory
Sisplatin
Treatment Outcome
Ultrasonography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Treatment options for isolated mediastinal lung cancer recurrence are limited. • EBUS guided intratumoral Cisplatin represents a novel therapeutic option. • 70% of treated patients achieved complete or partial remission in our series. • Patients who responded to therapy had higher overall and progression free survival. • Therapy was safe and well tolerated.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2015.10.009