Longitudinal disease- and steroid-related damage among adults with childhood-onset systemic lupus erythematosus

Determine whether adults with childhood-onset systemic lupus erythematosus (cSLE) are at increased risk for disease- and steroid-related damage as compared to individuals with adult-onset SLE (aSLE), and whether they continue to accumulate disease damage in adulthood. Data derive from the 2007–2015...

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Bibliographic Details
Published in:Seminars in arthritis and rheumatism 2019-10, Vol.49 (2), p.267-272
Main Authors: Heshin-Bekenstein, Merav, Trupin, Laura, Yelin, Ed, von Scheven, Emily, Yazdany, Jinoos, Lawson, Erica F.
Format: Article
Language:English
Subjects:
Adult-onset systemic lupus erythematosus
Brief Index of Lupus Damage (BILD) score
Childhood-onset systemic lupus erythematosus
Disease related damage
Steroid related damage
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Summary:Determine whether adults with childhood-onset systemic lupus erythematosus (cSLE) are at increased risk for disease- and steroid-related damage as compared to individuals with adult-onset SLE (aSLE), and whether they continue to accumulate disease damage in adulthood. Data derive from the 2007–2015 cycles of the Lupus Outcomes Study, a longitudinal cohort of adults with confirmed SLE. The Brief Index of Lupus Damage (BILD), a validated, patient-reported measure, was used to assess SLE-associated damage. Participants with baseline BILD were included (N = 1035). Diagnosis at age 
ISSN:0049-0172
1532-866X
DOI:10.1016/j.semarthrit.2019.05.010