Magnetic Nanoparticles in Cancer Therapy and Diagnosis

There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface‐area‐to‐volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can f...

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Bibliographic Details
Published in:Advanced healthcare materials 2020-05, Vol.9 (9), p.e1901058-n/a
Main Authors: Farzin, Ali, Etesami, Seyed Alireza, Quint, Jacob, Memic, Adnan, Tamayol, Ali
Format: Article
Language:English
Subjects:
Biomedical engineering
Biomedical materials
Biosensors
Cancer
cancer detection
Cancer therapies
cancer therapy
Contrast agents
Contrast Media
Diagnostic software
Diagnostic systems
Drug delivery
Drug Delivery Systems
Humans
Hyperthermia
Magnetic moments
magnetic nanoparticles
Magnetic Resonance Imaging
Magnetics
Magnetite Nanoparticles - therapeutic use
Nanomaterials
Nanoparticles
Nanotechnology
Neoplasms - diagnostic imaging
Neoplasms - therapy
Reagents
Therapy
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Summary:There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface‐area‐to‐volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can function as contrast agents for magnetic resonance imaging (MRI) and can improve the sensitivity of biosensors and diagnostic tools. Recent advancements in nanotechnology have resulted in the realization of the next generation of MNPs suitable for these and other biomedical applications. This review discusses methods utilized for the fabrication and engineering of MNPs. Recent progress in the use of MNPs for hyperthermia therapy, controlling drug release, MRI, and biosensing is also critically reviewed. Finally, challenges in the field and potential opportunities for the use of MNPs toward improving their properties are discussed. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface‐area‐to‐volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. They can improve the quality of magnetic resonance imaging (MRI) systems and the sensitivity of biosensors. In this review, the synthesis of various magnetic nanoparticles and their applications in diagnosis and treatment of cancerous tumors are discussed.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.201901058