Airborne Aerosolized Mouse Cytomegalovirus From Common Otolaryngology Procedures: Implications for COVID-19 Infection

Objectives To determine whether common otolaryngology procedures generate viable aerosolized virus through a murine cytomegalovirus (mCMV) model for infection. Study Design mCMV model of infection. Setting University of Utah laboratory. Methods Three-day-old BALB/c mice were inoculated with mCMV or...

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Bibliographic Details
Published in:Otolaryngology-head and neck surgery 2021-03, Vol.164 (3), p.547-555
Main Authors: Sayahi, Tofigh, Nielson, Christopher, Yu, Yuan, Neuberger, Kaden, Seipp, Michael, Firpo, Matthew A., Kelly, Kerry, Park, Albert H.
Format: Article
Language:English
Subjects:
aerosolization
Aerosols
aerosol‐generating procedure
Air Microbiology
airborne
Animals
COVID-19
cytomegalovirus
Mice
Mice, Inbred BALB C
Muromegalovirus - isolation & purification
otolaryngology surgical procedures
Otorhinolaryngologic Surgical Procedures
Special Section on COVID-19
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Summary:Objectives To determine whether common otolaryngology procedures generate viable aerosolized virus through a murine cytomegalovirus (mCMV) model for infection. Study Design mCMV model of infection. Setting University of Utah laboratory. Methods Three-day-old BALB/c mice were inoculated with mCMV or saline. Five days later, each mouse underwent drilling, microdebrider, coblation, and electrocautery procedures. Particle size distribution and PM2.5 (particulate matter
ISSN:0194-5998
1097-6817
DOI:10.1177/0194599820957966