The role of biosensors in coronavirus disease-2019 outbreak

Herein, we have summarized and argued about biomarkers and indicators used for the detection of severe acute respiratory syndrome coronavirus 2. Antibody detection methods are not considered suitable to screen individuals at early stages and asymptomatic cases. The diagnosis of coronavirus disease 2...

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Bibliographic Details
Published in:Current opinion in electrochemistry 2020-10, Vol.23, p.174-184
Main Authors: Asif, Muhammad, Ajmal, Muhammad, Ashraf, Ghazala, Muhammad, Nadeem, Aziz, Ayesha, Iftikhar, Tayyaba, Wang, Junlei, Liu, Hongfang
Format: Article
Language:English
Subjects:
Diagnostics
Electrochemical biosensors
Field-effect transistor biosensors
Plasmonic biosensors
Review
SARS-CoV-2
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Summary:Herein, we have summarized and argued about biomarkers and indicators used for the detection of severe acute respiratory syndrome coronavirus 2. Antibody detection methods are not considered suitable to screen individuals at early stages and asymptomatic cases. The diagnosis of coronavirus disease 2019 using biomarkers and indicators at point-of-care level is much crucial. Therefore, it is urgently needed to develop rapid and sensitive detection methods which can target antigens. We have critically elaborated key role of biosensors to cope the outbreak situation. In this review, the importance of biosensors including electrochemical, surface enhanced Raman scattering, field-effect transistor, and surface plasmon resonance biosensors in the detection of severe acute respiratory syndrome coronavirus 2 has been underscored. Finally, we have outlined pros and cons of diagnostic approaches and future directions. [Display omitted]
ISSN:2451-9103
2451-9111
DOI:10.1016/j.coelec.2020.08.011