Impact of Air Pollution on Asthma Outcomes

Asthma is a chronic respiratory disease characterized by variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air pollution has a negative impact on asthma outcomes in both adult and pediatric populations. The aim of this review is to summarize...

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Bibliographic Details
Published in:International journal of environmental research and public health 2020-08, Vol.17 (17), p.6212
Main Authors: Tiotiu, Angelica I., Novakova, Plamena, Nedeva, Denislava, Chong-Neto, Herberto Jose, Novakova, Silviya, Steiropoulos, Paschalis, Kowal, Krzysztof
Format: Article
Language:English
Subjects:
Age
Air flow
Air pollution
Air pollution measurements
Asthma
Carbon
Deoxyribonucleic acid
Disease prevention
DNA
Epigenetics
Exposure
Health risks
Indoor air pollution
Nitrogen dioxide
Outdoor air quality
Passive smoking
Pollutants
Pregnancy
Respiratory diseases
Respiratory function
Respiratory tract diseases
Review
Risk analysis
Risk factors
Signs and symptoms
Smoking
Tobacco
Tobacco smoking
VOCs
Volatile organic compounds
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Summary:Asthma is a chronic respiratory disease characterized by variable airflow obstruction, bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air pollution has a negative impact on asthma outcomes in both adult and pediatric populations. The aim of this review is to summarize the current knowledge on the effect of various outdoor and indoor pollutants on asthma outcomes, their burden on its management, as well as to highlight the measures that could result in improved asthma outcomes. Traffic-related air pollution, nitrogen dioxide and second-hand smoking (SHS) exposures represent significant risk factors for asthma development in children. Nevertheless, a causal relation between air pollution and development of adult asthma is not clearly established. Exposure to outdoor pollutants can induce asthma symptoms, exacerbations and decreases in lung function. Active tobacco smoking is associated with poorer asthma control, while exposure to SHS increases the risk of asthma exacerbations, respiratory symptoms and healthcare utilization. Other indoor pollutants such as heating sources and molds can also negatively impact the course of asthma. Global measures, that aim to reduce exposure to air pollutants, are highly needed in order to improve the outcomes and management of adult and pediatric asthma in addition to the existing guidelines.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph17176212