Neurological Disorders Identified during Treatment of a SARS-CoV-2 Infection

A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough refl...

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Bibliographic Details
Published in:Internal Medicine 2020/09/01, Vol.59(17), pp.2187-2189
Main Authors: Wada, Shinichi, Nagasaki, Yoji, Arimizu, Yoko, Shimo, Masatoshi, Matsukuma, Yuta, Okamoto, Masaki, Yoshida, Shinichiro, Ohashi, Ikkei, Hashimoto, Go, Kuwashiro, Takahiro, Yasaka, Masahiro, Okada, Yasushi
Format: Article
Language:English
Subjects:
acute disseminated encephalomyelitis
Aged
Betacoronavirus
Case Report
Coronavirus Infections - complications
Coronavirus Infections - epidemiology
Cough
COVID-19
Extubation
glycolipid antibody
Guillain-Barre syndrome
Guillain-Barre Syndrome - complications
Guillain-Barre Syndrome - diagnosis
Guillain-Barre Syndrome - drug therapy
Guillain-Barré syndrome
Humans
Immunoglobulins, Intravenous - therapeutic use
Internal medicine
Intravenous administration
intravenous immunoglobulin
Intubation
Male
Neurological diseases
Neurological disorders
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - epidemiology
Reflexes
SARS-CoV-2
Severe Acute Respiratory Syndrome - etiology
Severe Acute Respiratory Syndrome - therapy
Severe acute respiratory syndrome coronavirus 2
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Summary:A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). He underwent endotracheal intubation from Day 3. Although his respiratory condition improved and anesthetic drugs were discontinued, no cough reflex was observed despite intubation having been performed until Day 17. His tendon reflexes were also diminished. We suspected that he had developed Guillain-Barré syndrome (GBS), and administered intravenous immunoglobulin from Day 18. The absence of cough reflex improved and extubation was successfully performed on Day 23. Neurological disorders including GBS should be considered when intubated SARS-CoV-2 patients present with a loss of cough reflex during the treatment period.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.5447-20