Laparoscopic cytoreductive nephrectomy is associated with significantly improved survival compared with open cytoreductive nephrectomy or targeted therapy alone

The aim of the present study was to compare the survival outcomes for patients with metastatic renal cell carcinoma (mRCC) who underwent laparoscopic cytoreductive nephrectomy (CN) vs. open CN vs. targeted therapy (TT) alone at our institution. A retrospective chart review was performed at our insti...

Full description

Saved in:
Bibliographic Details
Published in:Molecular and clinical oncology 2020-12, Vol.13 (6), p.1-1
Main Authors: Zhao, Kaidong, Kim, Eric H, Vetter, Joel M, Hsieh, James J, Venkatesh, Ramakrishna, Bhayani, Sam B, Figenshau, R. Sherburne
Format: Article
Language:English
Subjects:
Analysis
Bias
Cancer metastasis
Cytokines
Hospitals
Immunotherapy
Kidney cancer
Laparoscopy
Medical prognosis
Metastasis
Oncology
Patient outcomes
Patients
Risk factors
Surgery
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of the present study was to compare the survival outcomes for patients with metastatic renal cell carcinoma (mRCC) who underwent laparoscopic cytoreductive nephrectomy (CN) vs. open CN vs. targeted therapy (TT) alone at our institution. A retrospective chart review was performed at our institution for patients who underwent CN prior to TT (laparoscopic, n=48; open, n=48) or who were deemed unfit for surgery and received TT alone (n=36), between January 2007 and December 2012. Kaplan-Meier estimated survival and Cox proportional hazards analyses were performed. Laparoscopic CN was associated with significantly longer survival compared with open CN or TT alone (median survival 24 vs.
ISSN:2049-9450
2049-9469
DOI:10.3892/mco.2020.2141