Continuous ablation improves lesion maturation compared with intermittent ablation strategies

Background Interrupted ablation is increasingly proposed as part of high‐power short‐duration radiofrequency ablation (RFA) strategies and may also result from loss of contact from respiratory patterns or cardiac motion. To study the extent that ablation interruption affects lesions. Methods In ex v...

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Bibliographic Details
Published in:Journal of cardiovascular electrophysiology 2020-07, Vol.31 (7), p.1687-1693
Main Authors: Rogers, Albert J., Borne, Ryan T., Ho, Grant, Sauer, William H., Wang, Paul J., Narayan, Sanjiv M., Zheng, Lijun, Nguyen, Duy T.
Format: Article
Language:English
Subjects:
Ablation
ablation biophysics
arrhythmia
catheter ablation
contact
interrupted
lesion formation
Lesions
Radiofrequency ablation
Respiration
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Summary:Background Interrupted ablation is increasingly proposed as part of high‐power short‐duration radiofrequency ablation (RFA) strategies and may also result from loss of contact from respiratory patterns or cardiac motion. To study the extent that ablation interruption affects lesions. Methods In ex vivo and in vivo experiments, lesion characteristics and tissue temperatures were compared between continuous (group 1) and interrupted (groups 2 and 3) RFA with equal total ablation duration and contact force. Extended duration ablation lesions were also characterized from 1 to 5 minutes. Results In the ex vivo study, continuous RFA (group 1) produced larger total lesion volumes compared with each interrupted ablation lesion group (273.8 ± 36.5 vs 205.1 ± 34.2 vs 174.3 ± 32.3 mm3, all P 
ISSN:1045-3873
1540-8167
DOI:10.1111/jce.14510