Rare case of docetaxel-induced myositis detected on fluorodeoxyglucose positron emission tomography/computed tomography in a patient with carcinoma breast

We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/com...

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Bibliographic Details
Published in:Indian journal of nuclear medicine 2020-07, Vol.35 (3), p.248-250
Main Authors: Parida, Girish, Upadhyay, Amitabh, Mitra, Sujata, Suman, Akchata, Muthu, Gopal
Format: Article
Language:English
Subjects:
Breast cancer
Carboplatin
Carcinoma
Chemotherapy
Computed tomography
Corticosteroids
Inflammatory diseases
Interesting Image
Muscles
Musculoskeletal diseases
Myositis
Positron emission
Tomography
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Summary:We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/computed tomography, of the underlying malignancy to the chemotherapeutic regimen, there was diffusely increased FDG uptake in the upper and lower limb muscles with associated painful, proximal muscle weakness. These symptoms regressed after the discontinuation of docetaxel and the administration of corticosteroids, suggesting it to be the drug-induced myositis.
ISSN:0972-3919
0974-0244
DOI:10.4103/ijnm.IJNM_25_20