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Rare case of docetaxel-induced myositis detected on fluorodeoxyglucose positron emission tomography/computed tomography in a patient with carcinoma breast

We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/com...

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Published in:Indian journal of nuclear medicine 2020-07, Vol.35 (3), p.248-250
Main Authors: Parida, Girish, Upadhyay, Amitabh, Mitra, Sujata, Suman, Akchata, Muthu, Gopal
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container_title Indian journal of nuclear medicine
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Upadhyay, Amitabh
Mitra, Sujata
Suman, Akchata
Muthu, Gopal
description We report an extremely rare case of acute inflammatory myopathy during combination chemotherapy with docetaxel and transtuzumab for metastatic breast carcinoma in a 44-year-old female patient. Despite the significant response in the follow-up fluorodeoxyglucose (FDG) positron emission tomography/computed tomography, of the underlying malignancy to the chemotherapeutic regimen, there was diffusely increased FDG uptake in the upper and lower limb muscles with associated painful, proximal muscle weakness. These symptoms regressed after the discontinuation of docetaxel and the administration of corticosteroids, suggesting it to be the drug-induced myositis.
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subjects Breast cancer
Carboplatin
Carcinoma
Chemotherapy
Computed tomography
Corticosteroids
Inflammatory diseases
Interesting Image
Muscles
Musculoskeletal diseases
Myositis
Positron emission
Tomography
title Rare case of docetaxel-induced myositis detected on fluorodeoxyglucose positron emission tomography/computed tomography in a patient with carcinoma breast
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