Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects

Epidemiological data predict a dramatic increase in the prevalence of diabetes and of diabetic retinopathy (DR) – the most common complication of diabetes-for which however we do not have so far effective tools for prevention and treatment. Since hypovitaminosis D is very frequent in patients with d...

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Published in:Reviews in endocrine & metabolic disorders 2021-12, Vol.22 (4), p.715-727
Main Authors: Tecilazich, Francesco, Formenti, Anna Maria, Giustina, Andrea
Format: Article
Language:English
Subjects:
Clinical aspects
Diabetes
Diabetes Mellitus
Diabetic retinopathy
Diabetic Retinopathy - epidemiology
Endocrinology
Epidemiology
Humans
Internal Medicine
Medicine
Medicine & Public Health
Patients
Randomized Controlled Trials as Topic
Retinopathy
Supplements
Vitamin D
Vitamin D - therapeutic use
Vitamin D Deficiency - complications
Vitamin D Deficiency - epidemiology
Vitamin deficiency
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creator Tecilazich, Francesco
Formenti, Anna Maria
Giustina, Andrea
description Epidemiological data predict a dramatic increase in the prevalence of diabetes and of diabetic retinopathy (DR) – the most common complication of diabetes-for which however we do not have so far effective tools for prevention and treatment. Since hypovitaminosis D is very frequent in patients with diabetes and vitamin D (VD) has vascular protective properties, several studies have addressed the association of VD deficiency with DR and its severity and progression, whereas the effects of VD supplementation on its natural history are largely unknown. Here we review the available evidence that supports the possible protective role of VD in DR and suggests to determine the VD levels in DR patients calling for a definitive randomized clinical trial to ascertain whether VD supplementation could protect against DR.
doi_str_mv 10.1007/s11154-020-09575-4
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subjects Clinical aspects
Diabetes
Diabetes Mellitus
Diabetic retinopathy
Diabetic Retinopathy - epidemiology
Endocrinology
Epidemiology
Humans
Internal Medicine
Medicine
Medicine & Public Health
Patients
Randomized Controlled Trials as Topic
Retinopathy
Supplements
Vitamin D
Vitamin D - therapeutic use
Vitamin D Deficiency - complications
Vitamin D Deficiency - epidemiology
Vitamin deficiency
title Role of vitamin D in diabetic retinopathy: Pathophysiological and clinical aspects
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