A case of dapsone-induced methaemoglobinaemia

Methaemoglobinaemia is an uncommon but potentially serious condition. It can be caused by congenital or acquired cause. Drug-induced methaemoglobinaemia is the commonest cause of acquired methaemoglobinaemia. The clinical signs and symptoms of methaemoglobinaemia include dyspnoea, desaturation, pres...

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Bibliographic Details
Published in:Clinical medicine (London, England) England), 2020-09, Vol.20 (5), p.519-521
Main Authors: Tan, Yee Ann, Ng, Kai Choon, Cheo, Seng Wee, Khoo, Tee Tat, Low, Qin Jian
Format: Article
Language:English
Subjects:
Acne
Acute Medical Care
Cyanosis
Dapsone
Disease prevention
Dyspnea
Hemoglobin
Hypoxia
methaemoglobinaemia
Patients
Pneumonia
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Summary:Methaemoglobinaemia is an uncommon but potentially serious condition. It can be caused by congenital or acquired cause. Drug-induced methaemoglobinaemia is the commonest cause of acquired methaemoglobinaemia. The clinical signs and symptoms of methaemoglobinaemia include dyspnoea, desaturation, presence of saturation gap, headache, nausea and seizures depending on level of serum methaemoglobinaemia. We illustrate a case of dapsone-induced methaemoglobinaemia and its successful treatment by intravenous methylene blue.
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmed.2020-0364