Surgical resection, intraoperative radiotherapy and immediate plastic reconstruction: A good option for the treatment of distal extremity soft tissue sarcomas

• Published in: Reports of practical oncology and radiotherapy 2020-11, Vol.25 (6), p.919-926
• Main Authors: Hanna, Samir Abdallah, Munhoz, Rodrigo Ramella, de Freitas Perina, André Luis, Gonçalves, Marina Sahade, da Costa, Fabio Paganini Pereira, de Freitas Busnardo, Fabio, de Oliveira Ferreira, Fabio
• Format: Article
• Language: English
• Subjects: Conservative approach; Intraoperative radiotherapy; Original; Soft tissue sarcomas
• ISSN: 1507-1367; 2083-4640
• DOI: 10.1016/j.rpor.2020.09.008

To show three patients with soft tissue sarcomas of distal extremities conservatively treated after tumor-board discussion, involving margin-free surgery, exclusive intraoperative radiotherapy, and immediate reconstruction. Current guidelines show clear and robust recommendations regarding the composition of the treatment of sarcomas of extremities. However, little evidence exists regarding the application of these treatments depending on the location of the primary neoplasia. Tumors that affect the distal extremities present different challenges and make multidisciplinary discussions desirable. We reported 3 patients who were approached with a conservative intention, after tumor board recomendation. The goals from the treatment performed were aesthetic and functional preservation, while enruring locoregional control. We had wound healing complications in 2 of the cases, requiring additional reconstruction measures. Patients are followed up for 24, 20 and 10 months; local control is 100%, and functional preservation is 100%. Despite being a small series, it was sufficient to illustrate successful multidisciplinary planning, generating a therapeutic result with improved quality of life for patients who had an initial indication for extremity amputation.