Green Synthesis of Lutein-Based Carbon Dots Applied for Free-Radical Scavenging within Cells

Reactive oxygen species (ROS) in the body play an important role in various processes. It is well known that harmful high levels of ROS can cause many problems in living organisms in a variety of ways. One effective way to remove intracellular ROS is to use reducing materials that can enter the cell...

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Bibliographic Details
Published in:Materials 2020-09, Vol.13 (18), p.4146
Main Authors: Yang, Dian, Li, Li, Cao, Lei, Chang, Zhimin, Mei, Qian, Yan, Ruhong, Ge, Mingfeng, Jiang, Chenyu, Dong, Wen-Fei
Format: Article
Language:English
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Summary:Reactive oxygen species (ROS) in the body play an important role in various processes. It is well known that harmful high levels of ROS can cause many problems in living organisms in a variety of ways. One effective way to remove intracellular ROS is to use reducing materials that can enter the cell. Herein, we developed a strong reducing carbon nano-dot from a natural product, lutein, as an initial raw material. This is a hydrothermal synthesis method with the advantages of simplicity, high yield, mild reaction conditions, and environmental friendliness. The prepared carbon dots exhibit bright blue fluorescence, and have good water solubility and biocompatibility. In particular, the carbon dots can easily enter the cell and effectively remove ROS. Therefore, the carbon dots are thought to protect cells from oxidative damage by high levels of ROS.
ISSN:1996-1944
1996-1944
DOI:10.3390/ma13184146