N-Iminopyridinium ylide-directed, cobalt-catalysed coupling of sp2 C–H bonds with alkynes

N-Iminopyridinium ylides are competent monodentate directing groups for cobalt-catalysed annulation of sp2 C–H bonds with internal alkynes. The pyridine moiety in the ylide serves as an internal oxidant and is cleaved during the reaction. The annulation reactions possess excellent compatibility with...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2020-09, Vol.56 (75), p.11070-11073
Main Authors: Kwak, Se Hun, Daugulis, Olafs
Format: Article
Language:English
Subjects:
Alkynes
Chemical reactions
Cobalt
Crystallography
Organic chemistry
Oxidizing agents
Pyrazole
Substrates
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:N-Iminopyridinium ylides are competent monodentate directing groups for cobalt-catalysed annulation of sp2 C–H bonds with internal alkynes. The pyridine moiety in the ylide serves as an internal oxidant and is cleaved during the reaction. The annulation reactions possess excellent compatibility with heterocyclic substrates, tolerating furan, thiophene, pyridine, pyrrole, pyrazole, and indole functionalities.
ISSN:1359-7345
1364-548X
DOI:10.1039/d0cc05294a