Loading…
Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T
Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic modality for characterisation of pancreatic lesions. Pancreatic MRI protocols are mostly qualitative due to time constraints and motion sensitivity. MR Fingerprinting is an innovative acquisition technique tha...
Saved in:
| Published in: | Scientific reports 2020-10, Vol.10 (1), p.17563-17563, Article 17563 |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093 |
| container_end_page | 17563 |
| container_issue | 1 |
| container_start_page | 17563 |
| container_title | Scientific reports |
| container_volume | 10 |
| creator | Serrao, Eva M. Kessler, Dimitri A. Carmo, Bruno Beer, Lucian Brindle, Kevin M. Buonincontri, Guido Gallagher, Ferdia A. Gilbert, Fiona J. Godfrey, Edmund Graves, Martin J. McLean, Mary A. Sala, Evis Schulte, Rolf F. Kaggie, Joshua D. |
| description | Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic modality for characterisation of pancreatic lesions. Pancreatic MRI protocols are mostly qualitative due to time constraints and motion sensitivity. MR Fingerprinting is an innovative acquisition technique that provides qualitative data and quantitative parameter maps from a single free‐breathing acquisition with the potential to reduce exam times. This work investigates the feasibility of MRF parameter mapping for pancreatic imaging in the presence of free-breathing exam. Sixteen healthy participants were prospectively imaged using MRF framework. Regions-of-interest were drawn in multiple solid organs including the pancreas and T
1
and T
2
values determined. MRF T
1
and T
2
mapping was performed successfully in all participants (acquisition time:2.4–3.6 min). Mean pancreatic T
1
values were 37–43% lower than those of the muscle, spleen, and kidney at both 1.5 and 3.0 T. For these organs, the mean pancreatic T
2
values were nearly 40% at 1.5 T and |
| doi_str_mv | 10.1038/s41598-020-74462-6 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7567885</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2451849241</sourcerecordid><originalsourceid>FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093</originalsourceid><addsrcrecordid>eNp9UctOwzAQtBCIVoUf4IB85JLid5wLEqooIIG4wNlynHVJ1TrFTpH4G76FL8MQQHDBF6-0s7OzMwgdUTKlhOvTJKisdEEYKUohFCvUDhozImTBOGO7v-oROkxpSfKTrBK02kcjzokqJZVjNL-1iwB963CE1AUbHGDfhgXETWxDnyvcedw_At7kXgSbsO0xncq313tsQ4P5lOTyAO15u0pw-PVP0MP84n52VdzcXV7Pzm8KlzX2hc7rfVk6VStVWQaWNzWBmjpudSOlkFLVuvG-8dIJyFdpzcF6ppq6LDmp-ASdDbybbb2GxkHoo12ZrHVt44vpbGv-dkL7aBbdsymlKrWWmeDkiyB2T1tIvVm3ycFqZQN022SYkFSLigmaoWyAutilFMH_rKHEfGRghgxMzsB8ZmBUHjr-LfBn5NvxDOADIH0YnH02y24bQzbtP9p3U52S5Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2451849241</pqid></control><display><type>article</type><title>Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T</title><source>Full-Text Journals in Chemistry (Open access)</source><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Serrao, Eva M. ; Kessler, Dimitri A. ; Carmo, Bruno ; Beer, Lucian ; Brindle, Kevin M. ; Buonincontri, Guido ; Gallagher, Ferdia A. ; Gilbert, Fiona J. ; Godfrey, Edmund ; Graves, Martin J. ; McLean, Mary A. ; Sala, Evis ; Schulte, Rolf F. ; Kaggie, Joshua D.</creator><creatorcontrib>Serrao, Eva M. ; Kessler, Dimitri A. ; Carmo, Bruno ; Beer, Lucian ; Brindle, Kevin M. ; Buonincontri, Guido ; Gallagher, Ferdia A. ; Gilbert, Fiona J. ; Godfrey, Edmund ; Graves, Martin J. ; McLean, Mary A. ; Sala, Evis ; Schulte, Rolf F. ; Kaggie, Joshua D.</creatorcontrib><description>Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic modality for characterisation of pancreatic lesions. Pancreatic MRI protocols are mostly qualitative due to time constraints and motion sensitivity. MR Fingerprinting is an innovative acquisition technique that provides qualitative data and quantitative parameter maps from a single free‐breathing acquisition with the potential to reduce exam times. This work investigates the feasibility of MRF parameter mapping for pancreatic imaging in the presence of free-breathing exam. Sixteen healthy participants were prospectively imaged using MRF framework. Regions-of-interest were drawn in multiple solid organs including the pancreas and T
1
and T
2
values determined. MRF T
1
and T
2
mapping was performed successfully in all participants (acquisition time:2.4–3.6 min). Mean pancreatic T
1
values were 37–43% lower than those of the muscle, spleen, and kidney at both 1.5 and 3.0 T. For these organs, the mean pancreatic T
2
values were nearly 40% at 1.5 T and < 12% at 3.0 T. The feasibility of MRF at 1.5 T and 3 T was demonstrated in the pancreas. By enabling fast and free-breathing quantitation, MRF has the potential to add value during the clinical characterisation and grading of pathological conditions, such as pancreatitis or cancer.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-020-74462-6</identifier><identifier>PMID: 33067515</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/308/53/2421 ; 692/700/1421 ; Adult ; Algorithms ; Female ; Humanities and Social Sciences ; Humans ; Image Processing, Computer-Assisted - methods ; Magnetic Resonance Imaging ; Male ; Motion ; multidisciplinary ; Pancreas - diagnostic imaging ; Pattern Recognition, Automated ; Phantoms, Imaging ; Prospective Studies ; Respiration ; Science ; Science (multidisciplinary)</subject><ispartof>Scientific reports, 2020-10, Vol.10 (1), p.17563-17563, Article 17563</ispartof><rights>The Author(s) 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093</citedby><cites>FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567885/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567885/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27915,27916,37004,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33067515$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Serrao, Eva M.</creatorcontrib><creatorcontrib>Kessler, Dimitri A.</creatorcontrib><creatorcontrib>Carmo, Bruno</creatorcontrib><creatorcontrib>Beer, Lucian</creatorcontrib><creatorcontrib>Brindle, Kevin M.</creatorcontrib><creatorcontrib>Buonincontri, Guido</creatorcontrib><creatorcontrib>Gallagher, Ferdia A.</creatorcontrib><creatorcontrib>Gilbert, Fiona J.</creatorcontrib><creatorcontrib>Godfrey, Edmund</creatorcontrib><creatorcontrib>Graves, Martin J.</creatorcontrib><creatorcontrib>McLean, Mary A.</creatorcontrib><creatorcontrib>Sala, Evis</creatorcontrib><creatorcontrib>Schulte, Rolf F.</creatorcontrib><creatorcontrib>Kaggie, Joshua D.</creatorcontrib><title>Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic modality for characterisation of pancreatic lesions. Pancreatic MRI protocols are mostly qualitative due to time constraints and motion sensitivity. MR Fingerprinting is an innovative acquisition technique that provides qualitative data and quantitative parameter maps from a single free‐breathing acquisition with the potential to reduce exam times. This work investigates the feasibility of MRF parameter mapping for pancreatic imaging in the presence of free-breathing exam. Sixteen healthy participants were prospectively imaged using MRF framework. Regions-of-interest were drawn in multiple solid organs including the pancreas and T
1
and T
2
values determined. MRF T
1
and T
2
mapping was performed successfully in all participants (acquisition time:2.4–3.6 min). Mean pancreatic T
1
values were 37–43% lower than those of the muscle, spleen, and kidney at both 1.5 and 3.0 T. For these organs, the mean pancreatic T
2
values were nearly 40% at 1.5 T and < 12% at 3.0 T. The feasibility of MRF at 1.5 T and 3 T was demonstrated in the pancreas. By enabling fast and free-breathing quantitation, MRF has the potential to add value during the clinical characterisation and grading of pathological conditions, such as pancreatitis or cancer.</description><subject>692/308/53/2421</subject><subject>692/700/1421</subject><subject>Adult</subject><subject>Algorithms</subject><subject>Female</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Motion</subject><subject>multidisciplinary</subject><subject>Pancreas - diagnostic imaging</subject><subject>Pattern Recognition, Automated</subject><subject>Phantoms, Imaging</subject><subject>Prospective Studies</subject><subject>Respiration</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9UctOwzAQtBCIVoUf4IB85JLid5wLEqooIIG4wNlynHVJ1TrFTpH4G76FL8MQQHDBF6-0s7OzMwgdUTKlhOvTJKisdEEYKUohFCvUDhozImTBOGO7v-oROkxpSfKTrBK02kcjzokqJZVjNL-1iwB963CE1AUbHGDfhgXETWxDnyvcedw_At7kXgSbsO0xncq313tsQ4P5lOTyAO15u0pw-PVP0MP84n52VdzcXV7Pzm8KlzX2hc7rfVk6VStVWQaWNzWBmjpudSOlkFLVuvG-8dIJyFdpzcF6ppq6LDmp-ASdDbybbb2GxkHoo12ZrHVt44vpbGv-dkL7aBbdsymlKrWWmeDkiyB2T1tIvVm3ycFqZQN022SYkFSLigmaoWyAutilFMH_rKHEfGRghgxMzsB8ZmBUHjr-LfBn5NvxDOADIH0YnH02y24bQzbtP9p3U52S5Q</recordid><startdate>20201016</startdate><enddate>20201016</enddate><creator>Serrao, Eva M.</creator><creator>Kessler, Dimitri A.</creator><creator>Carmo, Bruno</creator><creator>Beer, Lucian</creator><creator>Brindle, Kevin M.</creator><creator>Buonincontri, Guido</creator><creator>Gallagher, Ferdia A.</creator><creator>Gilbert, Fiona J.</creator><creator>Godfrey, Edmund</creator><creator>Graves, Martin J.</creator><creator>McLean, Mary A.</creator><creator>Sala, Evis</creator><creator>Schulte, Rolf F.</creator><creator>Kaggie, Joshua D.</creator><general>Nature Publishing Group UK</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20201016</creationdate><title>Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T</title><author>Serrao, Eva M. ; Kessler, Dimitri A. ; Carmo, Bruno ; Beer, Lucian ; Brindle, Kevin M. ; Buonincontri, Guido ; Gallagher, Ferdia A. ; Gilbert, Fiona J. ; Godfrey, Edmund ; Graves, Martin J. ; McLean, Mary A. ; Sala, Evis ; Schulte, Rolf F. ; Kaggie, Joshua D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>692/308/53/2421</topic><topic>692/700/1421</topic><topic>Adult</topic><topic>Algorithms</topic><topic>Female</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Motion</topic><topic>multidisciplinary</topic><topic>Pancreas - diagnostic imaging</topic><topic>Pattern Recognition, Automated</topic><topic>Phantoms, Imaging</topic><topic>Prospective Studies</topic><topic>Respiration</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Serrao, Eva M.</creatorcontrib><creatorcontrib>Kessler, Dimitri A.</creatorcontrib><creatorcontrib>Carmo, Bruno</creatorcontrib><creatorcontrib>Beer, Lucian</creatorcontrib><creatorcontrib>Brindle, Kevin M.</creatorcontrib><creatorcontrib>Buonincontri, Guido</creatorcontrib><creatorcontrib>Gallagher, Ferdia A.</creatorcontrib><creatorcontrib>Gilbert, Fiona J.</creatorcontrib><creatorcontrib>Godfrey, Edmund</creatorcontrib><creatorcontrib>Graves, Martin J.</creatorcontrib><creatorcontrib>McLean, Mary A.</creatorcontrib><creatorcontrib>Sala, Evis</creatorcontrib><creatorcontrib>Schulte, Rolf F.</creatorcontrib><creatorcontrib>Kaggie, Joshua D.</creatorcontrib><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Serrao, Eva M.</au><au>Kessler, Dimitri A.</au><au>Carmo, Bruno</au><au>Beer, Lucian</au><au>Brindle, Kevin M.</au><au>Buonincontri, Guido</au><au>Gallagher, Ferdia A.</au><au>Gilbert, Fiona J.</au><au>Godfrey, Edmund</au><au>Graves, Martin J.</au><au>McLean, Mary A.</au><au>Sala, Evis</au><au>Schulte, Rolf F.</au><au>Kaggie, Joshua D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2020-10-16</date><risdate>2020</risdate><volume>10</volume><issue>1</issue><spage>17563</spage><epage>17563</epage><pages>17563-17563</pages><artnum>17563</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic modality for characterisation of pancreatic lesions. Pancreatic MRI protocols are mostly qualitative due to time constraints and motion sensitivity. MR Fingerprinting is an innovative acquisition technique that provides qualitative data and quantitative parameter maps from a single free‐breathing acquisition with the potential to reduce exam times. This work investigates the feasibility of MRF parameter mapping for pancreatic imaging in the presence of free-breathing exam. Sixteen healthy participants were prospectively imaged using MRF framework. Regions-of-interest were drawn in multiple solid organs including the pancreas and T
1
and T
2
values determined. MRF T
1
and T
2
mapping was performed successfully in all participants (acquisition time:2.4–3.6 min). Mean pancreatic T
1
values were 37–43% lower than those of the muscle, spleen, and kidney at both 1.5 and 3.0 T. For these organs, the mean pancreatic T
2
values were nearly 40% at 1.5 T and < 12% at 3.0 T. The feasibility of MRF at 1.5 T and 3 T was demonstrated in the pancreas. By enabling fast and free-breathing quantitation, MRF has the potential to add value during the clinical characterisation and grading of pathological conditions, such as pancreatitis or cancer.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>33067515</pmid><doi>10.1038/s41598-020-74462-6</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2045-2322 |
| ispartof | Scientific reports, 2020-10, Vol.10 (1), p.17563-17563, Article 17563 |
| issn | 2045-2322 2045-2322 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7567885 |
| source | Full-Text Journals in Chemistry (Open access); Publicly Available Content (ProQuest); PubMed Central; Springer Nature - nature.com Journals - Fully Open Access |
| subjects | 692/308/53/2421 692/700/1421 Adult Algorithms Female Humanities and Social Sciences Humans Image Processing, Computer-Assisted - methods Magnetic Resonance Imaging Male Motion multidisciplinary Pancreas - diagnostic imaging Pattern Recognition, Automated Phantoms, Imaging Prospective Studies Respiration Science Science (multidisciplinary) |
| title | Magnetic resonance fingerprinting of the pancreas at 1.5 T and 3.0 T |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T22%3A21%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Magnetic%20resonance%20fingerprinting%20of%20the%20pancreas%20at%201.5%C2%A0T%20and%203.0%C2%A0T&rft.jtitle=Scientific%20reports&rft.au=Serrao,%20Eva%20M.&rft.date=2020-10-16&rft.volume=10&rft.issue=1&rft.spage=17563&rft.epage=17563&rft.pages=17563-17563&rft.artnum=17563&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/s41598-020-74462-6&rft_dat=%3Cproquest_pubme%3E2451849241%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c446t-8419f77c6b669a2ea3db0eb1c3a8d554556b8dffdf5c4e462883eaf26db773093%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2451849241&rft_id=info:pmid/33067515&rfr_iscdi=true |