Parvovirus B19 infection mimicking systemic lupus erythematosus, successfully treated with intravenous immune globulin

Parvovirus B19 infection generally presents as a transient viral illness in children but rarely shows systemic lupus erythematosus-like symptoms. Here we present a 7-year-old girl with parvovirus B19 infection who had prolonged fever, rash, pancytopenia and hypocomplementemia making it difficult do...

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Bibliographic Details
Published in:Germs (Bucureşti) 2020-09, Vol.10 (3), p.244-248
Main Authors: Özlü, Sare Gülfem, Alan, Başak, Şahiner, Aysegül, Bulut, Büşra, Bayhan, Gülsüm İclal, Özdemir, Sonay İncesoy
Format: Article
Language:English
Subjects:
Alopecia
Anemia
Antibodies
Arthritis
Baldness
Blood
Case Report
Enzymes
Fever
Infection
Infections
Infectious diseases
Intravenous immunoglobulins
Laboratories
Leukopenia
Lupus
Patients
Raynaud disease
Systemic lupus erythematosus
Thrombocytopenia
Viral infections
Virus diseases
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Summary:Parvovirus B19 infection generally presents as a transient viral illness in children but rarely shows systemic lupus erythematosus-like symptoms. Here we present a 7-year-old girl with parvovirus B19 infection who had prolonged fever, rash, pancytopenia and hypocomplementemia making it difficult do differentiate from the first episode of systemic lupus erythematosus. Because she had severe progressive pancytopenia she was administered intravenous immune globulin treatment and her clinical course was dramatically improved. Parvovirus B19 infection can mimic systemic lupus erythematosus and it may be difficult to differentiate a recent parvovirus B19 infection and the first presentation of systemic lupus erythematosus. Absence of discoid lesions, alopecia, Raynaud phenomenon and autoimmune hemolytic anemia may help to distinguish parvovirus B19 infection from systemic lupus erythematosus. Parvovirus B19 infection may cause a severe clinical picture resembling systemic lupus erythematosus even in otherwise healthy children. Intravenous immune globulin treatment might be considered in cases resistant to supportive management.
ISSN:2248-2997
2248-2997
DOI:10.18683/germs.2020.1211