Association of Multidrug Resistance Gene-1 (MDR1 C1236T) Polymorphism with the Risk of Acute Myeloid Leukemia in a Moroccan Population

The human multidrug resistance MDR1 gene plays a crucial role in the absorption, transport, metabolism and elimination of harmful compounds. An impaired metabolism of these compounds related to genetic polymorphism may cause cancer such as acute myeloid leukemia AML.

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Bibliographic Details
Published in:Asian Pacific journal of cancer prevention : APJCP 2020-07, Vol.21 (7), p.1899-1904
Main Authors: Boujmia, Oum Kaltoum Ait, Nadifi, Sellama, Dehbi, Hind, Lamchahab, Mouna, Quessar, Asma
Format: Article
Language:English
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Description
Summary:The human multidrug resistance MDR1 gene plays a crucial role in the absorption, transport, metabolism and elimination of harmful compounds. An impaired metabolism of these compounds related to genetic polymorphism may cause cancer such as acute myeloid leukemia AML.
ISSN:1513-7368
2476-762X
DOI:10.31557/APJCP.2020.21.7.1899