Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome

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Bibliographic Details
Published in:Blood 2020-10, Vol.136 (17), p.1980-1983
Main Authors: Zhang, Qian, Orlando, Elena J., Wang, Hong Y., Bogusz, Agata M., Liu, Xiaobin, Lacey, Simon F., Strauser, Honore T., Nunez-Cruz, Selene, Nejati, Reza, Zhang, Paul, Brooks, Sarah, Watt, Christopher, Melenhorst, J. Joseph, June, Carl H., Schuster, Stephen J., Wasik, Mariusz A.
Format: Article
Language:English
Subjects:
Adenine - administration & dosage
Adenine - adverse effects
Adenine - analogs & derivatives
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Cell Transdifferentiation - genetics
Cell Transdifferentiation - immunology
Cellular Reprogramming - genetics
Cellular Reprogramming - immunology
Cellular Reprogramming - physiology
Combined Modality Therapy
Epigenesis, Genetic - physiology
Epigenome - immunology
Gene Rearrangement
Genes, Immunoglobulin Heavy Chain - genetics
Humans
Immunotherapy - adverse effects
Immunotherapy - methods
Letter to
Lymph Nodes - pathology
Lymphoma, Mantle-Cell - genetics
Lymphoma, Mantle-Cell - immunology
Lymphoma, Mantle-Cell - therapy
Neoplasms, Second Primary - diagnosis
Neoplasms, Second Primary - etiology
Piperidines - administration & dosage
Piperidines - adverse effects
Receptors, Antigen, T-Cell - therapeutic use
Rituximab - administration & dosage
Rituximab - adverse effects
Sarcoma - etiology
Sarcoma - genetics
Sarcoma - immunology
Sarcoma - pathology
Transplantation, Autologous - adverse effects
Tumor Cells, Cultured
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ISSN:0006-4971
1528-0020
DOI:10.1182/blood.2020005123