Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human

Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia,...

Full description

Saved in:
Bibliographic Details
Published in:Nutrients 2020-10, Vol.12 (10), p.3080
Main Authors: Jee, Hye Jin, Lee, Sang Goo, Bormate, Katrina Joy, Jung, Yi-Sook
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Alzheimer's disease
Caffeine
Caffeine - administration & dosage
Caffeine - adverse effects
Caffeine - poisoning
Caffeine - therapeutic use
Caffeinism
Coffee
Dose-Response Relationship, Drug
Female
Gastrointestinal diseases
Gender
Gender differences
Humans
Insomnia
Male
Mental disorders
Mental Disorders - etiology
Mental Disorders - prevention & control
Middle Aged
Mortality
Nervous System Diseases - etiology
Nervous System Diseases - prevention & control
Neurological diseases
Precision medicine
Review
Risk analysis
Risk Assessment
Risk Factors
Sex Characteristics
Sex differences
Signs and symptoms
Sleep disorders
Tea
Womens health
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33
cites cdi_FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33
container_end_page
container_issue 10
container_start_page 3080
container_title Nutrients
container_volume 12
creator Jee, Hye Jin
Lee, Sang Goo
Bormate, Katrina Joy
Jung, Yi-Sook
description Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. Recently, there has been increasing interest in the effect of caffeine consumption as a protective factor or risk factor for neurological and psychiatric disorders. Currently, the importance of personalized medicine is being emphasized, and research on sex/gender differences needs to be conducted. Our review focuses on the effect of caffeine consumption on several neurological and psychiatric disorders with respect to sex differences to provide a better understanding of caffeine use as a risk or protective factor for those disorders. The findings may help establish new strategies for developing sex-specific caffeine therapies.
doi_str_mv 10.3390/nu12103080
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7601837</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2535312356</sourcerecordid><originalsourceid>FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33</originalsourceid><addsrcrecordid>eNpVUdtKLDEQDHJERX3xAyTg24HVzrSTzPggHNb1AqLi5Tlksx03upusyYzo3xvxepqGrqaL6oJibEvALmILe6EXlQCEBpbYWgWqGki5j39-4VW2mfMDvJcCJXGFrSJCDSjqNRZHzpHteHR8aAr0gfgwhtzPF52PgZfupsSvfX7kLiZ-QX2Ks3jvrZlxEyb8Kr_aqTdd8pYf-RzThFI-4Df0UtYimChYytwHftrPTdhgy87MMm1-znV2dzy6HZ4Ozi9Pzob_zgd2H2Q3kHVtnalaoUAo1ZIZAzZSQGNbU40b5VwrGjM2rSwn1SAo0ZCoScrWTBwhrrPDD91FP57TxFLokpnpRfJzk151NF7_fwl-qu_js1YSRIOqCOx8CqT41FPu9EPsUyiedVVjjaLCWhbW3w-WTTHnRO77gwD9no_-yaeQt397-qZ-pYFvEWOLpA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2535312356</pqid></control><display><type>article</type><title>Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human</title><source>Publicly Available Content Database</source><source>PubMed Central</source><creator>Jee, Hye Jin ; Lee, Sang Goo ; Bormate, Katrina Joy ; Jung, Yi-Sook</creator><creatorcontrib>Jee, Hye Jin ; Lee, Sang Goo ; Bormate, Katrina Joy ; Jung, Yi-Sook</creatorcontrib><description>Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. Recently, there has been increasing interest in the effect of caffeine consumption as a protective factor or risk factor for neurological and psychiatric disorders. Currently, the importance of personalized medicine is being emphasized, and research on sex/gender differences needs to be conducted. Our review focuses on the effect of caffeine consumption on several neurological and psychiatric disorders with respect to sex differences to provide a better understanding of caffeine use as a risk or protective factor for those disorders. The findings may help establish new strategies for developing sex-specific caffeine therapies.</description><identifier>ISSN: 2072-6643</identifier><identifier>EISSN: 2072-6643</identifier><identifier>DOI: 10.3390/nu12103080</identifier><identifier>PMID: 33050315</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Alzheimer's disease ; Caffeine ; Caffeine - administration &amp; dosage ; Caffeine - adverse effects ; Caffeine - poisoning ; Caffeine - therapeutic use ; Caffeinism ; Coffee ; Dose-Response Relationship, Drug ; Female ; Gastrointestinal diseases ; Gender ; Gender differences ; Humans ; Insomnia ; Male ; Mental disorders ; Mental Disorders - etiology ; Mental Disorders - prevention &amp; control ; Middle Aged ; Mortality ; Nervous System Diseases - etiology ; Nervous System Diseases - prevention &amp; control ; Neurological diseases ; Precision medicine ; Review ; Risk analysis ; Risk Assessment ; Risk Factors ; Sex Characteristics ; Sex differences ; Signs and symptoms ; Sleep disorders ; Tea ; Womens health ; Young Adult</subject><ispartof>Nutrients, 2020-10, Vol.12 (10), p.3080</ispartof><rights>2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 by the authors. 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33</citedby><cites>FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2535312356/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2535312356?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,25734,27905,27906,36993,44571,53772,53774,74875</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33050315$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jee, Hye Jin</creatorcontrib><creatorcontrib>Lee, Sang Goo</creatorcontrib><creatorcontrib>Bormate, Katrina Joy</creatorcontrib><creatorcontrib>Jung, Yi-Sook</creatorcontrib><title>Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human</title><title>Nutrients</title><addtitle>Nutrients</addtitle><description>Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. Recently, there has been increasing interest in the effect of caffeine consumption as a protective factor or risk factor for neurological and psychiatric disorders. Currently, the importance of personalized medicine is being emphasized, and research on sex/gender differences needs to be conducted. Our review focuses on the effect of caffeine consumption on several neurological and psychiatric disorders with respect to sex differences to provide a better understanding of caffeine use as a risk or protective factor for those disorders. The findings may help establish new strategies for developing sex-specific caffeine therapies.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alzheimer's disease</subject><subject>Caffeine</subject><subject>Caffeine - administration &amp; dosage</subject><subject>Caffeine - adverse effects</subject><subject>Caffeine - poisoning</subject><subject>Caffeine - therapeutic use</subject><subject>Caffeinism</subject><subject>Coffee</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Gastrointestinal diseases</subject><subject>Gender</subject><subject>Gender differences</subject><subject>Humans</subject><subject>Insomnia</subject><subject>Male</subject><subject>Mental disorders</subject><subject>Mental Disorders - etiology</subject><subject>Mental Disorders - prevention &amp; control</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Nervous System Diseases - etiology</subject><subject>Nervous System Diseases - prevention &amp; control</subject><subject>Neurological diseases</subject><subject>Precision medicine</subject><subject>Review</subject><subject>Risk analysis</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Sex Characteristics</subject><subject>Sex differences</subject><subject>Signs and symptoms</subject><subject>Sleep disorders</subject><subject>Tea</subject><subject>Womens health</subject><subject>Young Adult</subject><issn>2072-6643</issn><issn>2072-6643</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNpVUdtKLDEQDHJERX3xAyTg24HVzrSTzPggHNb1AqLi5Tlksx03upusyYzo3xvxepqGrqaL6oJibEvALmILe6EXlQCEBpbYWgWqGki5j39-4VW2mfMDvJcCJXGFrSJCDSjqNRZHzpHteHR8aAr0gfgwhtzPF52PgZfupsSvfX7kLiZ-QX2Ks3jvrZlxEyb8Kr_aqTdd8pYf-RzThFI-4Df0UtYimChYytwHftrPTdhgy87MMm1-znV2dzy6HZ4Ozi9Pzob_zgd2H2Q3kHVtnalaoUAo1ZIZAzZSQGNbU40b5VwrGjM2rSwn1SAo0ZCoScrWTBwhrrPDD91FP57TxFLokpnpRfJzk151NF7_fwl-qu_js1YSRIOqCOx8CqT41FPu9EPsUyiedVVjjaLCWhbW3w-WTTHnRO77gwD9no_-yaeQt397-qZ-pYFvEWOLpA</recordid><startdate>20201009</startdate><enddate>20201009</enddate><creator>Jee, Hye Jin</creator><creator>Lee, Sang Goo</creator><creator>Bormate, Katrina Joy</creator><creator>Jung, Yi-Sook</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20201009</creationdate><title>Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human</title><author>Jee, Hye Jin ; Lee, Sang Goo ; Bormate, Katrina Joy ; Jung, Yi-Sook</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alzheimer's disease</topic><topic>Caffeine</topic><topic>Caffeine - administration &amp; dosage</topic><topic>Caffeine - adverse effects</topic><topic>Caffeine - poisoning</topic><topic>Caffeine - therapeutic use</topic><topic>Caffeinism</topic><topic>Coffee</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Gastrointestinal diseases</topic><topic>Gender</topic><topic>Gender differences</topic><topic>Humans</topic><topic>Insomnia</topic><topic>Male</topic><topic>Mental disorders</topic><topic>Mental Disorders - etiology</topic><topic>Mental Disorders - prevention &amp; control</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Nervous System Diseases - etiology</topic><topic>Nervous System Diseases - prevention &amp; control</topic><topic>Neurological diseases</topic><topic>Precision medicine</topic><topic>Review</topic><topic>Risk analysis</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Sex Characteristics</topic><topic>Sex differences</topic><topic>Signs and symptoms</topic><topic>Sleep disorders</topic><topic>Tea</topic><topic>Womens health</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jee, Hye Jin</creatorcontrib><creatorcontrib>Lee, Sang Goo</creatorcontrib><creatorcontrib>Bormate, Katrina Joy</creatorcontrib><creatorcontrib>Jung, Yi-Sook</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Physical Education Index</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nutrients</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jee, Hye Jin</au><au>Lee, Sang Goo</au><au>Bormate, Katrina Joy</au><au>Jung, Yi-Sook</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human</atitle><jtitle>Nutrients</jtitle><addtitle>Nutrients</addtitle><date>2020-10-09</date><risdate>2020</risdate><volume>12</volume><issue>10</issue><spage>3080</spage><pages>3080-</pages><issn>2072-6643</issn><eissn>2072-6643</eissn><abstract>Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been used safely as a mild stimulant for a long time. However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. Recently, there has been increasing interest in the effect of caffeine consumption as a protective factor or risk factor for neurological and psychiatric disorders. Currently, the importance of personalized medicine is being emphasized, and research on sex/gender differences needs to be conducted. Our review focuses on the effect of caffeine consumption on several neurological and psychiatric disorders with respect to sex differences to provide a better understanding of caffeine use as a risk or protective factor for those disorders. The findings may help establish new strategies for developing sex-specific caffeine therapies.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>33050315</pmid><doi>10.3390/nu12103080</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2072-6643
ispartof Nutrients, 2020-10, Vol.12 (10), p.3080
issn 2072-6643
2072-6643
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7601837
source Publicly Available Content Database; PubMed Central
subjects Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Alzheimer's disease
Caffeine
Caffeine - administration & dosage
Caffeine - adverse effects
Caffeine - poisoning
Caffeine - therapeutic use
Caffeinism
Coffee
Dose-Response Relationship, Drug
Female
Gastrointestinal diseases
Gender
Gender differences
Humans
Insomnia
Male
Mental disorders
Mental Disorders - etiology
Mental Disorders - prevention & control
Middle Aged
Mortality
Nervous System Diseases - etiology
Nervous System Diseases - prevention & control
Neurological diseases
Precision medicine
Review
Risk analysis
Risk Assessment
Risk Factors
Sex Characteristics
Sex differences
Signs and symptoms
Sleep disorders
Tea
Womens health
Young Adult
title Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T16%3A54%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Caffeine%20Consumption%20on%20the%20Risk%20for%20Neurological%20and%20Psychiatric%20Disorders:%20Sex%20Differences%20in%20Human&rft.jtitle=Nutrients&rft.au=Jee,%20Hye%20Jin&rft.date=2020-10-09&rft.volume=12&rft.issue=10&rft.spage=3080&rft.pages=3080-&rft.issn=2072-6643&rft.eissn=2072-6643&rft_id=info:doi/10.3390/nu12103080&rft_dat=%3Cproquest_pubme%3E2535312356%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c406t-655cfa291701779eab0386108c9a2b87ff918aba96eab7830718e15e669adfe33%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2535312356&rft_id=info:pmid/33050315&rfr_iscdi=true