Potential of therapeutic plasmapheresis in treatment of COVID-19 patients: Immunopathogenesis and coagulopathy

Therapeutic plasmapheresis (TP) is the process of the separation and removal of plasma from other blood components and is considered as an adjunctive treatment strategy to the discarded abnormal agent in the management of respiratory viral pandemics. This article reviews the mechanisms of immunopath...

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Bibliographic Details
Published in:Transfusion and apheresis science 2020-12, Vol.59 (6), p.102993-102993, Article 102993
Main Authors: Balagholi, Sahar, Dabbaghi, Rasul, Eshghi, Peyman, Mousavi, Seyed Asadollah, Heshmati, Farhad, Mohammadi, Saeed
Format: Article
Language:English
Subjects:
Blood Coagulation Disorders - economics
Blood Coagulation Disorders - epidemiology
Blood Coagulation Disorders - therapy
Coagulopathy
COVID-19
COVID-19 - blood
COVID-19 - complications
COVID-19 - epidemiology
COVID-19 - therapy
Health technology assessment
Humans
Immunopathogenesis
Pandemics
Plasma Exchange
Plasmapheresis
SARS-CoV-2
Therapeutic Plasmapheresis
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Summary:Therapeutic plasmapheresis (TP) is the process of the separation and removal of plasma from other blood components and is considered as an adjunctive treatment strategy to the discarded abnormal agent in the management of respiratory viral pandemics. This article reviews the mechanisms of immunopathogenesis and coagulopathy induced by SARS-CoV-2 and the potential benefits of TP as adjunctive treatment in critically COVID-19 patients.
ISSN:1473-0502
1878-1683
1473-0502
DOI:10.1016/j.transci.2020.102993