Developing Collaborative Platforms to Advance Neurotechnology and Its Translation

Neurotechnological devices are failing to deliver on their therapeutic promise because of the time it takes to translate them from bench to clinic. In this Perspective, we reflect on lessons learned from medical device successes and failures and consider how such lessons might shape a strategic visi...

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Bibliographic Details
Published in:Neuron (Cambridge, Mass.) Mass.), 2020-10, Vol.108 (2), p.286-301
Main Authors: Borton, David A., Dawes, Heather E., Worrell, Gregory A., Starr, Philip A., Denison, Timothy J.
Format: Article
Language:English
Subjects:
Biomedical Research - organization & administration
Biotechnology - organization & administration
Brain research
Collaboration
Consumer electronics
Disease
Dyskinesia
Economics
Humans
Information Dissemination
Innovations
Intervention
Medical equipment
Medical technology
Neurosciences - instrumentation
Neurosciences - methods
Neurosciences - organization & administration
Patients
Pharmaceuticals
R&D
Regulatory approval
Research & development
Translational Research, Biomedical - organization & administration
Transplants & implants
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Summary:Neurotechnological devices are failing to deliver on their therapeutic promise because of the time it takes to translate them from bench to clinic. In this Perspective, we reflect on lessons learned from medical device successes and failures and consider how such lessons might shape a strategic vision for translating neurotechnologies in the future. We articulate how the intentional design and deployment of “scientific platforms,” from the technology stack of hardware and software through the supporting ecosystem, could catalyze a new wave of innovation, discovery, and therapy. We also identify specific actions that could promote future neurotechnology roadmaps and industrial-academic-government collaborative activities. We believe that community-supported neurotechnology platforms will prove to be transformational in accelerating ideas from bench to bedside, maximizing scientific discovery and improving patient care. In their Perspective, Borton et al. describe the opportunities and challenges of scientific platforms to help catalyze translation of clinical neuroscience to therapeutic interventions.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2020.10.001