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In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database
Objectives We aimed to assess the in‐hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD). Background There is lack of data on the outcomes of PMVR for mitral regurgitation in pat...
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| Published in: | Catheterization and cardiovascular interventions 2021-01, Vol.97 (1), p.E104-E112 |
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| creator | Osman, Mohammed Khan, Muhammad Zia Farjo, Peter D. Khan, Muhammad U. Khan, Safi U. Benjamin, Mina M. Munir, Muhammad Bilal Balla, Sudarshan |
| description | Objectives
We aimed to assess the in‐hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD).
Background
There is lack of data on the outcomes of PMVR for mitral regurgitation in patients with COPD.
Methods
We analyzed the national inpatient sample (NIS) database from January 2012 to December 2016.
Results
A total of 9125 patients underwent PMVR in the period between January 2012 and December 2016, of whom 2,495 (27.3%) patients had concomitant COPD. Comparing COPD patients to non‐COPD patients, COPD patients had higher proportion of females (48.3% vs. 46.6%, p = .16), were younger (75.8 ± 10.0 years vs. 76.4 ± 12.2 years; p = .04), had higher prevalence of peripheral vascular disease (17.4% vs. 13.5%; p |
| doi_str_mv | 10.1002/ccd.28913 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7644582</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2478480092</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4433-510f86ed476f904de5779bd7b9e4a2059c4a980d6461fd04491e007cf1fc19213</originalsourceid><addsrcrecordid>eNp1kctu1TAQhiMEohdY8ALIEhu6OK3tOLHNAgkdbpUqsQGJneU4k8ZVEgfbOVV3PAJvwXvxJEzJoQIkVrY033yamb8onjB6yijlZ861p1xpVt4rDlnF-Uby-vP9_Z9pUR8URyldUUp1zfXD4qDkpRRalIfF9_Ppx9dvfUizz3YgYckujJBI6MgM0S3ZThCWREafI9Z3dtgBiTBbH4mfyGyzhykncu1zT1wfw-QdCU3KcXHZIzsvwxgmG29I6xPYBC-wL_nLHpu6GEaSeyATahAasLQ3kmTHeQDS2mwb7HpUPOjskODx_j0uPr1983H7fnPx4d359tXFxglRlpuK0U7V0ApZd5qKFiopddPKRoOwnFbaCasVbWtRs66lQmgGlErXsc4xzVl5XLxcvfPSjNA6HAX3NnP0I-5ggvXm78rke3MZdkbWQlSKo-D5XhDDlwVSNqNPDoZhPaThpdaqVFIpRJ_9g16FJeIZkBJSCYV53QpPVsrFkFKE7m4YRs1t_AbjN7_iR_bpn9Pfkb_zRuBsBa79ADf_N5nt9vWq_AklB7-j</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2478480092</pqid></control><display><type>article</type><title>In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database</title><source>Wiley</source><creator>Osman, Mohammed ; Khan, Muhammad Zia ; Farjo, Peter D. ; Khan, Muhammad U. ; Khan, Safi U. ; Benjamin, Mina M. ; Munir, Muhammad Bilal ; Balla, Sudarshan</creator><creatorcontrib>Osman, Mohammed ; Khan, Muhammad Zia ; Farjo, Peter D. ; Khan, Muhammad U. ; Khan, Safi U. ; Benjamin, Mina M. ; Munir, Muhammad Bilal ; Balla, Sudarshan</creatorcontrib><description><![CDATA[Objectives
We aimed to assess the in‐hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD).
Background
There is lack of data on the outcomes of PMVR for mitral regurgitation in patients with COPD.
Methods
We analyzed the national inpatient sample (NIS) database from January 2012 to December 2016.
Results
A total of 9125 patients underwent PMVR in the period between January 2012 and December 2016, of whom 2,495 (27.3%) patients had concomitant COPD. Comparing COPD patients to non‐COPD patients, COPD patients had higher proportion of females (48.3% vs. 46.6%, p = .16), were younger (75.8 ± 10.0 years vs. 76.4 ± 12.2 years; p = .04), had higher prevalence of peripheral vascular disease (17.4% vs. 13.5%; p < .01) and renal failure (39.3% vs. 37%; p < .01). After propensity matching, there was no significant difference in mortality among the COPD group versus non‐COPD patients (2.6% vs. 2.9%; p = .6). Patients with COPD had higher proportion of in‐hospital morbidities including St‐segment elevation myocardial infarction (1.8% vs. 1.0%; p = .02), cardiogenic shock (1.4% vs. 0.4%; p < .01), vascular complications (2% vs. 0.8; p < .01), pneumothorax (1% vs. 0.4%; p < .01), and septic shock (1.2% vs. 0.4%; p < .01). Moreover, surrogates of severe disability (mechanical intubation and non‐home discharges), cost of hospitalization, and length of stay were higher in the COPD group.
Conclusions
There was no difference in mortality between the COPD and non‐COPD patients after PMVR. Moreover, we observed higher rates of in‐hospital morbidities, surrogates of severe disability, and higher resources utilization by the COPD group.]]></description><identifier>ISSN: 1522-1946</identifier><identifier>EISSN: 1522-726X</identifier><identifier>DOI: 10.1002/ccd.28913</identifier><identifier>PMID: 32374943</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Chronic obstructive pulmonary disease ; Female ; Heart Valve Prosthesis Implantation ; Hospital Mortality ; Hospitals ; Humans ; Inpatients ; Intubation ; Lung diseases ; mitral clip ; mitral regurgitation ; Mitral valve ; Mitral Valve - diagnostic imaging ; Mitral Valve - surgery ; Mitral Valve Insufficiency - diagnostic imaging ; Mitral Valve Insufficiency - epidemiology ; Mitral Valve Insufficiency - surgery ; Mortality ; Myocardial infarction ; national in‐patient sample database ; Obstructive lung disease ; percutaneous mitral valve repair ; Pneumothorax ; Pulmonary Disease, Chronic Obstructive - diagnosis ; Pulmonary Disease, Chronic Obstructive - epidemiology ; Regurgitation ; Renal failure ; Septic shock ; Treatment Outcome ; Vascular diseases</subject><ispartof>Catheterization and cardiovascular interventions, 2021-01, Vol.97 (1), p.E104-E112</ispartof><rights>2020 Wiley Periodicals, Inc.</rights><rights>2021 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4433-510f86ed476f904de5779bd7b9e4a2059c4a980d6461fd04491e007cf1fc19213</citedby><cites>FETCH-LOGICAL-c4433-510f86ed476f904de5779bd7b9e4a2059c4a980d6461fd04491e007cf1fc19213</cites><orcidid>0000-0001-5097-5568 ; 0000-0003-1559-6911 ; 0000-0001-9076-2321</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32374943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Osman, Mohammed</creatorcontrib><creatorcontrib>Khan, Muhammad Zia</creatorcontrib><creatorcontrib>Farjo, Peter D.</creatorcontrib><creatorcontrib>Khan, Muhammad U.</creatorcontrib><creatorcontrib>Khan, Safi U.</creatorcontrib><creatorcontrib>Benjamin, Mina M.</creatorcontrib><creatorcontrib>Munir, Muhammad Bilal</creatorcontrib><creatorcontrib>Balla, Sudarshan</creatorcontrib><title>In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database</title><title>Catheterization and cardiovascular interventions</title><addtitle>Catheter Cardiovasc Interv</addtitle><description><![CDATA[Objectives
We aimed to assess the in‐hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD).
Background
There is lack of data on the outcomes of PMVR for mitral regurgitation in patients with COPD.
Methods
We analyzed the national inpatient sample (NIS) database from January 2012 to December 2016.
Results
A total of 9125 patients underwent PMVR in the period between January 2012 and December 2016, of whom 2,495 (27.3%) patients had concomitant COPD. Comparing COPD patients to non‐COPD patients, COPD patients had higher proportion of females (48.3% vs. 46.6%, p = .16), were younger (75.8 ± 10.0 years vs. 76.4 ± 12.2 years; p = .04), had higher prevalence of peripheral vascular disease (17.4% vs. 13.5%; p < .01) and renal failure (39.3% vs. 37%; p < .01). After propensity matching, there was no significant difference in mortality among the COPD group versus non‐COPD patients (2.6% vs. 2.9%; p = .6). Patients with COPD had higher proportion of in‐hospital morbidities including St‐segment elevation myocardial infarction (1.8% vs. 1.0%; p = .02), cardiogenic shock (1.4% vs. 0.4%; p < .01), vascular complications (2% vs. 0.8; p < .01), pneumothorax (1% vs. 0.4%; p < .01), and septic shock (1.2% vs. 0.4%; p < .01). Moreover, surrogates of severe disability (mechanical intubation and non‐home discharges), cost of hospitalization, and length of stay were higher in the COPD group.
Conclusions
There was no difference in mortality between the COPD and non‐COPD patients after PMVR. Moreover, we observed higher rates of in‐hospital morbidities, surrogates of severe disability, and higher resources utilization by the COPD group.]]></description><subject>Chronic obstructive pulmonary disease</subject><subject>Female</subject><subject>Heart Valve Prosthesis Implantation</subject><subject>Hospital Mortality</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Inpatients</subject><subject>Intubation</subject><subject>Lung diseases</subject><subject>mitral clip</subject><subject>mitral regurgitation</subject><subject>Mitral valve</subject><subject>Mitral Valve - diagnostic imaging</subject><subject>Mitral Valve - surgery</subject><subject>Mitral Valve Insufficiency - diagnostic imaging</subject><subject>Mitral Valve Insufficiency - epidemiology</subject><subject>Mitral Valve Insufficiency - surgery</subject><subject>Mortality</subject><subject>Myocardial infarction</subject><subject>national in‐patient sample database</subject><subject>Obstructive lung disease</subject><subject>percutaneous mitral valve repair</subject><subject>Pneumothorax</subject><subject>Pulmonary Disease, Chronic Obstructive - diagnosis</subject><subject>Pulmonary Disease, Chronic Obstructive - epidemiology</subject><subject>Regurgitation</subject><subject>Renal failure</subject><subject>Septic shock</subject><subject>Treatment Outcome</subject><subject>Vascular diseases</subject><issn>1522-1946</issn><issn>1522-726X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kctu1TAQhiMEohdY8ALIEhu6OK3tOLHNAgkdbpUqsQGJneU4k8ZVEgfbOVV3PAJvwXvxJEzJoQIkVrY033yamb8onjB6yijlZ861p1xpVt4rDlnF-Uby-vP9_Z9pUR8URyldUUp1zfXD4qDkpRRalIfF9_Ppx9dvfUizz3YgYckujJBI6MgM0S3ZThCWREafI9Z3dtgBiTBbH4mfyGyzhykncu1zT1wfw-QdCU3KcXHZIzsvwxgmG29I6xPYBC-wL_nLHpu6GEaSeyATahAasLQ3kmTHeQDS2mwb7HpUPOjskODx_j0uPr1983H7fnPx4d359tXFxglRlpuK0U7V0ApZd5qKFiopddPKRoOwnFbaCasVbWtRs66lQmgGlErXsc4xzVl5XLxcvfPSjNA6HAX3NnP0I-5ggvXm78rke3MZdkbWQlSKo-D5XhDDlwVSNqNPDoZhPaThpdaqVFIpRJ_9g16FJeIZkBJSCYV53QpPVsrFkFKE7m4YRs1t_AbjN7_iR_bpn9Pfkb_zRuBsBa79ADf_N5nt9vWq_AklB7-j</recordid><startdate>20210101</startdate><enddate>20210101</enddate><creator>Osman, Mohammed</creator><creator>Khan, Muhammad Zia</creator><creator>Farjo, Peter D.</creator><creator>Khan, Muhammad U.</creator><creator>Khan, Safi U.</creator><creator>Benjamin, Mina M.</creator><creator>Munir, Muhammad Bilal</creator><creator>Balla, Sudarshan</creator><general>John Wiley & Sons, Inc</general><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5097-5568</orcidid><orcidid>https://orcid.org/0000-0003-1559-6911</orcidid><orcidid>https://orcid.org/0000-0001-9076-2321</orcidid></search><sort><creationdate>20210101</creationdate><title>In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database</title><author>Osman, Mohammed ; Khan, Muhammad Zia ; Farjo, Peter D. ; Khan, Muhammad U. ; Khan, Safi U. ; Benjamin, Mina M. ; Munir, Muhammad Bilal ; Balla, Sudarshan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4433-510f86ed476f904de5779bd7b9e4a2059c4a980d6461fd04491e007cf1fc19213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Chronic obstructive pulmonary disease</topic><topic>Female</topic><topic>Heart Valve Prosthesis Implantation</topic><topic>Hospital Mortality</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Inpatients</topic><topic>Intubation</topic><topic>Lung diseases</topic><topic>mitral clip</topic><topic>mitral regurgitation</topic><topic>Mitral valve</topic><topic>Mitral Valve - diagnostic imaging</topic><topic>Mitral Valve - surgery</topic><topic>Mitral Valve Insufficiency - diagnostic imaging</topic><topic>Mitral Valve Insufficiency - epidemiology</topic><topic>Mitral Valve Insufficiency - surgery</topic><topic>Mortality</topic><topic>Myocardial infarction</topic><topic>national in‐patient sample database</topic><topic>Obstructive lung disease</topic><topic>percutaneous mitral valve repair</topic><topic>Pneumothorax</topic><topic>Pulmonary Disease, Chronic Obstructive - diagnosis</topic><topic>Pulmonary Disease, Chronic Obstructive - epidemiology</topic><topic>Regurgitation</topic><topic>Renal failure</topic><topic>Septic shock</topic><topic>Treatment Outcome</topic><topic>Vascular diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Osman, Mohammed</creatorcontrib><creatorcontrib>Khan, Muhammad Zia</creatorcontrib><creatorcontrib>Farjo, Peter D.</creatorcontrib><creatorcontrib>Khan, Muhammad U.</creatorcontrib><creatorcontrib>Khan, Safi U.</creatorcontrib><creatorcontrib>Benjamin, Mina M.</creatorcontrib><creatorcontrib>Munir, Muhammad Bilal</creatorcontrib><creatorcontrib>Balla, Sudarshan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Osman, Mohammed</au><au>Khan, Muhammad Zia</au><au>Farjo, Peter D.</au><au>Khan, Muhammad U.</au><au>Khan, Safi U.</au><au>Benjamin, Mina M.</au><au>Munir, Muhammad Bilal</au><au>Balla, Sudarshan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Catheter Cardiovasc Interv</addtitle><date>2021-01-01</date><risdate>2021</risdate><volume>97</volume><issue>1</issue><spage>E104</spage><epage>E112</epage><pages>E104-E112</pages><issn>1522-1946</issn><eissn>1522-726X</eissn><abstract><![CDATA[Objectives
We aimed to assess the in‐hospital outcomes in patients with mitral regurgitation treated with percutaneous mitral valve repair (PMVR) among patients with chronic obstructive pulmonary disease (COPD).
Background
There is lack of data on the outcomes of PMVR for mitral regurgitation in patients with COPD.
Methods
We analyzed the national inpatient sample (NIS) database from January 2012 to December 2016.
Results
A total of 9125 patients underwent PMVR in the period between January 2012 and December 2016, of whom 2,495 (27.3%) patients had concomitant COPD. Comparing COPD patients to non‐COPD patients, COPD patients had higher proportion of females (48.3% vs. 46.6%, p = .16), were younger (75.8 ± 10.0 years vs. 76.4 ± 12.2 years; p = .04), had higher prevalence of peripheral vascular disease (17.4% vs. 13.5%; p < .01) and renal failure (39.3% vs. 37%; p < .01). After propensity matching, there was no significant difference in mortality among the COPD group versus non‐COPD patients (2.6% vs. 2.9%; p = .6). Patients with COPD had higher proportion of in‐hospital morbidities including St‐segment elevation myocardial infarction (1.8% vs. 1.0%; p = .02), cardiogenic shock (1.4% vs. 0.4%; p < .01), vascular complications (2% vs. 0.8; p < .01), pneumothorax (1% vs. 0.4%; p < .01), and septic shock (1.2% vs. 0.4%; p < .01). Moreover, surrogates of severe disability (mechanical intubation and non‐home discharges), cost of hospitalization, and length of stay were higher in the COPD group.
Conclusions
There was no difference in mortality between the COPD and non‐COPD patients after PMVR. Moreover, we observed higher rates of in‐hospital morbidities, surrogates of severe disability, and higher resources utilization by the COPD group.]]></abstract><cop>Hoboken, USA</cop><pub>John Wiley & Sons, Inc</pub><pmid>32374943</pmid><doi>10.1002/ccd.28913</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-5097-5568</orcidid><orcidid>https://orcid.org/0000-0003-1559-6911</orcidid><orcidid>https://orcid.org/0000-0001-9076-2321</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Wiley |
| subjects | Chronic obstructive pulmonary disease Female Heart Valve Prosthesis Implantation Hospital Mortality Hospitals Humans Inpatients Intubation Lung diseases mitral clip mitral regurgitation Mitral valve Mitral Valve - diagnostic imaging Mitral Valve - surgery Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - epidemiology Mitral Valve Insufficiency - surgery Mortality Myocardial infarction national in‐patient sample database Obstructive lung disease percutaneous mitral valve repair Pneumothorax Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - epidemiology Regurgitation Renal failure Septic shock Treatment Outcome Vascular diseases |
| title | In‐hospital outcomes of percutaneous mitral valve repair in patients with chronic obstructive pulmonary disease: insights from the national inpatient sample database |
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