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Potentially Reversible and Recognizable Acute Encephalopathic Syndromes: Disease Categorization and MRI Appearances
"Encephalopathy" is a vague term that encompasses varying definitions, often with a nonspecific clinical presentation and numerous possible pathophysiologic causes. Hence, MR imaging plays a crucial role in the early diagnosis and treatment by identifying imaging patterns when there is lim...
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Published in: | American journal of neuroradiology : AJNR 2020-08, Vol.41 (8), p.1328-1338 |
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description | "Encephalopathy" is a vague term that encompasses varying definitions, often with a nonspecific clinical presentation and numerous possible pathophysiologic causes. Hence, MR imaging plays a crucial role in the early diagnosis and treatment by identifying imaging patterns when there is limited clinical history in such patients with acute encephalopathy. The aim of this review was to aid in remembrance of etiologies of potentially reversible acute encephalopathic syndromes on MR imaging. The differential includes vascular (reversible cerebral vasoconstriction syndrome, transient global amnesia, disseminated intravascular coagulation, and thrombotic microangiopathy), infection (meningitis, encephalitis), toxic (posterior reversible encephalopathy syndrome, acute toxic leukoencephalopathy; carbon monoxide, alcohol-related, medication- and illicit drug-related toxic encephalopathies), autoimmune, metabolic (osmotic demyelination syndrome, uremic, acute hepatic encephalopathy), idiopathic/inflammatory (stroke-like migraine attacks after radiation therapy syndrome), neoplasm-related encephalopathy, and seizure-related encephalopathy. |
doi_str_mv | 10.3174/ajnr.A6634 |
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The differential includes vascular (reversible cerebral vasoconstriction syndrome, transient global amnesia, disseminated intravascular coagulation, and thrombotic microangiopathy), infection (meningitis, encephalitis), toxic (posterior reversible encephalopathy syndrome, acute toxic leukoencephalopathy; carbon monoxide, alcohol-related, medication- and illicit drug-related toxic encephalopathies), autoimmune, metabolic (osmotic demyelination syndrome, uremic, acute hepatic encephalopathy), idiopathic/inflammatory (stroke-like migraine attacks after radiation therapy syndrome), neoplasm-related encephalopathy, and seizure-related encephalopathy.</description><identifier>ISSN: 0195-6108</identifier><identifier>EISSN: 1936-959X</identifier><identifier>DOI: 10.3174/ajnr.A6634</identifier><identifier>PMID: 32616580</identifier><language>eng</language><publisher>United States: American Society of Neuroradiology</publisher><subject>Adult Brain ; Diagnosis, Differential ; Female ; Humans ; Magnetic Resonance Imaging - methods ; Male ; Posterior Leukoencephalopathy Syndrome - diagnostic imaging ; Posterior Leukoencephalopathy Syndrome - etiology</subject><ispartof>American journal of neuroradiology : AJNR, 2020-08, Vol.41 (8), p.1328-1338</ispartof><rights>2020 by American Journal of Neuroradiology.</rights><rights>2020 by American Journal of Neuroradiology 2020 American Journal of Neuroradiology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0003-2530-5970</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658879/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7658879/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32616580$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Koksel, Y</creatorcontrib><creatorcontrib>McKinney, A M</creatorcontrib><title>Potentially Reversible and Recognizable Acute Encephalopathic Syndromes: Disease Categorization and MRI Appearances</title><title>American journal of neuroradiology : AJNR</title><addtitle>AJNR Am J Neuroradiol</addtitle><description>"Encephalopathy" is a vague term that encompasses varying definitions, often with a nonspecific clinical presentation and numerous possible pathophysiologic causes. 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The differential includes vascular (reversible cerebral vasoconstriction syndrome, transient global amnesia, disseminated intravascular coagulation, and thrombotic microangiopathy), infection (meningitis, encephalitis), toxic (posterior reversible encephalopathy syndrome, acute toxic leukoencephalopathy; carbon monoxide, alcohol-related, medication- and illicit drug-related toxic encephalopathies), autoimmune, metabolic (osmotic demyelination syndrome, uremic, acute hepatic encephalopathy), idiopathic/inflammatory (stroke-like migraine attacks after radiation therapy syndrome), neoplasm-related encephalopathy, and seizure-related encephalopathy.</description><subject>Adult Brain</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Posterior Leukoencephalopathy Syndrome - diagnostic imaging</subject><subject>Posterior Leukoencephalopathy Syndrome - etiology</subject><issn>0195-6108</issn><issn>1936-959X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpVkN9KwzAUh4Mobk5vfADpC3SmSZq0XghlTh1MlKngXTlNky3SJSXpBvPprX_Rq8M5h-_jnB9Cpwke00Swc3i1flxwTtkeGiY55XGe5i_7aIiTPI15grMBOgrhFWOc5oIcogElPOFphocoPLhO2c5A0-yihdoqH0zVqAhs3bfSLa15g49BITediqZWqnYFjWuhWxkZPe5s7d1ahYvoygQFQUUT6NTS-R7rjLOforvFLCraVoGHng_H6EBDE9TJdx2h5-vp0-Q2nt_fzCbFPG4J513c38gIxYIQCSkXgnKV66xKJBCWAehaYwKMplUNUmMtmZBUM5rJjGuFKaMjdPnlbTfVWtWy_9NDU7berMHvSgem_L-xZlUu3bYUfTaZyHvB2V_BL_kTH30HKNd1fg</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Koksel, Y</creator><creator>McKinney, A M</creator><general>American Society of Neuroradiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2530-5970</orcidid></search><sort><creationdate>202008</creationdate><title>Potentially Reversible and Recognizable Acute Encephalopathic Syndromes: Disease Categorization and MRI Appearances</title><author>Koksel, Y ; McKinney, A M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p266t-2614230722ca567736e9f8b1ca248aafdf02a435bdacf0fc47c3f438c86fe0343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Adult Brain</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Posterior Leukoencephalopathy Syndrome - diagnostic imaging</topic><topic>Posterior Leukoencephalopathy Syndrome - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Koksel, Y</creatorcontrib><creatorcontrib>McKinney, A M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of neuroradiology : AJNR</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Koksel, Y</au><au>McKinney, A M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Potentially Reversible and Recognizable Acute Encephalopathic Syndromes: Disease Categorization and MRI Appearances</atitle><jtitle>American journal of neuroradiology : AJNR</jtitle><addtitle>AJNR Am J Neuroradiol</addtitle><date>2020-08</date><risdate>2020</risdate><volume>41</volume><issue>8</issue><spage>1328</spage><epage>1338</epage><pages>1328-1338</pages><issn>0195-6108</issn><eissn>1936-959X</eissn><abstract>"Encephalopathy" is a vague term that encompasses varying definitions, often with a nonspecific clinical presentation and numerous possible pathophysiologic causes. Hence, MR imaging plays a crucial role in the early diagnosis and treatment by identifying imaging patterns when there is limited clinical history in such patients with acute encephalopathy. The aim of this review was to aid in remembrance of etiologies of potentially reversible acute encephalopathic syndromes on MR imaging. The differential includes vascular (reversible cerebral vasoconstriction syndrome, transient global amnesia, disseminated intravascular coagulation, and thrombotic microangiopathy), infection (meningitis, encephalitis), toxic (posterior reversible encephalopathy syndrome, acute toxic leukoencephalopathy; carbon monoxide, alcohol-related, medication- and illicit drug-related toxic encephalopathies), autoimmune, metabolic (osmotic demyelination syndrome, uremic, acute hepatic encephalopathy), idiopathic/inflammatory (stroke-like migraine attacks after radiation therapy syndrome), neoplasm-related encephalopathy, and seizure-related encephalopathy.</abstract><cop>United States</cop><pub>American Society of Neuroradiology</pub><pmid>32616580</pmid><doi>10.3174/ajnr.A6634</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2530-5970</orcidid></addata></record> |
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subjects | Adult Brain Diagnosis, Differential Female Humans Magnetic Resonance Imaging - methods Male Posterior Leukoencephalopathy Syndrome - diagnostic imaging Posterior Leukoencephalopathy Syndrome - etiology |
title | Potentially Reversible and Recognizable Acute Encephalopathic Syndromes: Disease Categorization and MRI Appearances |
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