Mean arterial pressure is associated with the neurological function in patients who survived after cardiopulmonary resuscitation: A retrospective cohort study

Background About 18% to 40% of the survivors have moderate to severe neurological dysfunction. At present, studies on mean arterial pressure (MAP) and neurological function of patients survived after cardiopulmonary resuscitation (CPR) are limited and conflicted. Hypothesis The higher the MAP of the...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2020-11, Vol.43 (11), p.1286-1293
Main Authors: Ai, Hai‐bo, Jiang, En‐li, Yu, Ji‐hua, Xiong, Lin‐bo, Yang, Qi, Jin, Qi‐zu, Gong, Wen‐yan, Chen, Shuai, Zhang, Hong
Format: Article
Language:English
Subjects:
Age
Cardiopulmonary resuscitation
Cardiovascular disease
Chronic illnesses
Chronic obstructive pulmonary disease
Clinical Investigations
Cohort analysis
Coronary vessels
CPR
Diabetes
Drug dosages
Epidemiology
Etiology
Heart failure
Hospitals
Hypertension
Hypoxia
Ischemia
Kidneys
mean arterial pressure
neurological function
Physiology
Regression analysis
Renal replacement therapy
Variables
Ventilators
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Summary:Background About 18% to 40% of the survivors have moderate to severe neurological dysfunction. At present, studies on mean arterial pressure (MAP) and neurological function of patients survived after cardiopulmonary resuscitation (CPR) are limited and conflicted. Hypothesis The higher the MAP of the patient who survived after CPR, the better the neurological function. Method A retrospective cohort study was conducted to detect the relationship between MAP and the neurological function of patients who survived after CPR by univariate analysis, multivariate regression analysis, and subgroup analysis. Results From January 2007 to December 2015, a total of 290 cases met the inclusion criteria and were enrolled in this study. The univariate analysis showed that MAP was associated with the neurological function of patients who survived after CPR; its OR value was 1.03 (1.01, 1.04). The multi‐factor regression analysis also showed that MAP was associated with the neurological function of patients survived after CPR in the four models, the adjusted OR value of the four models were 1.021 (1.008, 1.035); 1.028 (1.013, 1.043); 1.027 (1.012, 1.043); and 1.029 (1.014, 1.044), respectively. The subgroups analyses showed that when 65 mm Hg ≤ MAP
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23441