Prevalence and associated factors of glaucoma in the Russian Ural Eye and Medical Study

To assess the prevalence and associated factors of glaucoma in a Russian population. The population-based Ural Eye and Medical Study included 5899 (mean age 59.0 ± 10.7 years; range 40–94 years). Glaucomatous optic neuropathy was diagnosed using International Society of Geographical and Epidemiologi...

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Bibliographic Details
Published in:Scientific reports 2020-11, Vol.10 (1), p.20307-20307, Article 20307
Main Authors: Bikbov, Mukharram M., Gilmanshin, Timur R., Zainullin, Rinat M., Kazakbaeva, Gyulli M., Arslangareeva, Inga I., Panda-Jonas, Songhomitra, Khikmatullin, Renat I., Aminev, Said K., Nuriev, Ildar F., Zaynetdinov, Artur F., Uzianbaeva, Yulia V., Nikitin, Nikolay A., Mukhamadieva, Svetlana R., Yakupova, Dilya F., Rakhimova, Ellina M., Rusakova, Iulia A., Bolshakova, Natalia I., Safiullina, Kamila R., Jonas, Jost B.
Format: Article
Language:English
Subjects:
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692/700
Adult
Age
Age Distribution
Age Factors
Aged
Aged, 80 and over
Anterior chamber
Bashkiria - epidemiology
Blindness
Blood pressure
Epidemiology
Female
Glaucoma
Glaucoma, Angle-Closure - complications
Glaucoma, Angle-Closure - diagnosis
Glaucoma, Angle-Closure - drug therapy
Glaucoma, Angle-Closure - epidemiology
Glaucoma, Open-Angle - complications
Glaucoma, Open-Angle - diagnosis
Glaucoma, Open-Angle - drug therapy
Glaucoma, Open-Angle - epidemiology
Humanities and Social Sciences
Humans
Intraocular Pressure
Male
Middle Aged
multidisciplinary
Optic Nerve Diseases - diagnosis
Optic Nerve Diseases - epidemiology
Optic Nerve Diseases - etiology
Optic neuropathy
Prevalence
Science
Science (multidisciplinary)
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Summary:To assess the prevalence and associated factors of glaucoma in a Russian population. The population-based Ural Eye and Medical Study included 5899 (mean age 59.0 ± 10.7 years; range 40–94 years). Glaucomatous optic neuropathy was diagnosed using International Society of Geographical and Epidemiological Ophthalmology (ISGEO) criteria. Among 5545 participants with assessable optic disc photographs, 246 individuals [4.4%; 95% confidence interval (CI) 3.9, 5.0] had glaucoma, with open-angle glaucoma (OAG) in 177 individuals (3.2%; 95% CI 2.7, 3.7) and angle-closure glaucoma (ACG) in 69 individuals (1.2; 95% CI 1.0, 1.5), with IOP > 21 mmHg in 79 (32.1%) patients, and with 80 (32.5%) patients on glaucoma therapy. Glaucoma prevalence increased from 3/485 (0.6%; 95% CI 0.0, 1.3) in the age group of 40–45 years to 33/165 (20.0%; 95% CI 13.8, 26.2) in the group aged 80 + years. Higher OAG prevalence correlated with older age [odds ratio (OR) 1.07; 95% CI 1.04, 1.09; P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-77344-z