Glycosylated fibronectin point‐of‐care test for diagnosis of pre‐eclampsia in a low‐resource setting: a prospective Southeast Asian population study

Objective To determine the performance of a glycosylated fibronectin (GlyFn) point‐of‐care (POC) test for pre‐eclampsia (PE) in a large Southeast Asian cohort (India) in comparison to previously described biomarkers. Design A total of 798 pregnant women at ≥20 weeks of gestation were enrolled in a p...

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Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2020-12, Vol.127 (13), p.1687-1694
Main Authors: Nagalla, SR, Janaki, V, Vijayalakshmi, AR, Chayadevi, K, Pratibha, D, Rao, PV, Sage, KM, Nair‐Schaef, D, Bean, E, Roberts, CT, Gravett, MG
Format: Article
Language:English
Subjects:
Adult
Biomarkers
Case-Control Studies
Cohort Studies
Creatinine
Diagnosis
Eclampsia
Female
Fibronectin
Fibronectins - blood
Gestation
Gestational hypertension
Glycation End Products, Advanced
glycosylated fibronectin
Health Resources
Humans
Hypertension
India
Maternal Medicine
Medical diagnosis
Placenta
Point-of-Care Systems
point‐of‐care test
Population studies
Poverty
Pre-Eclampsia - blood
Pre-Eclampsia - diagnosis
Preeclampsia
Pregnancy
pre‐eclampsia
Prospective Studies
Protein-tyrosine kinase
Proteins
Young Adult
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Summary:Objective To determine the performance of a glycosylated fibronectin (GlyFn) point‐of‐care (POC) test for pre‐eclampsia (PE) in a large Southeast Asian cohort (India) in comparison to previously described biomarkers. Design A total of 798 pregnant women at ≥20 weeks of gestation were enrolled in a prospective case‐control study. Study participants included 469 normotensive women with urinary mg protein/mmol creatinine ratio
ISSN:1470-0328
1471-0528
DOI:10.1111/1471-0528.16323