Towards detection of brain injury using multimodal non-invasive neuromonitoring in adults undergoing extracorporeal membrane oxygenation

Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary bypass that provides life-saving support to critically ill patients whose illness is progressing despite maximal conventional support. Use in adults is expanding, however neurological injuries are common. Currently, the existing...

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Bibliographic Details
Published in:Biomedical optics express 2020-11, Vol.11 (11), p.6551-6569
Main Authors: Dar, Irfaan A., Khan, Imad R., Maddox, Ross K., Selioutski, Olga, Donohue, Kelly L., Marinescu, Mark A., Prasad, Sunil M., Quazi, Nadim H., Donlon, Jack S., Loose, Emily A., Ramirez, Gabriel A., Ren, Jingxuan, Majeski, Joseph B., Abramson, Kenneth, Durduran, Turgut, Busch, David R., Choe, Regine
Format: Article
Language:English
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Summary:Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary bypass that provides life-saving support to critically ill patients whose illness is progressing despite maximal conventional support. Use in adults is expanding, however neurological injuries are common. Currently, the existing brain imaging tools are a snapshot in time and require high-risk patient transport. Here we assess the feasibility of measuring diffuse correlation spectroscopy, transcranial Doppler ultrasound, electroencephalography, and auditory brainstem responses at the bedside, and developing a cerebral autoregulation metric. We report preliminary results from two patients, demonstrating feasibility and laying the foundation for future studies monitoring neurological health during ECMO.
ISSN:2156-7085
2156-7085
DOI:10.1364/BOE.401641