PATENT DUCTUS ARTERIOSUS CLOSURE: EXPERIENCE FROM A TERTIARY REFERRAL CENTER

ABSTRACT Objective: To characterize the number and methods of closure of Persistent Ductus Arteriosus (PDA) over a span of 16 years in a third level maternity hospital. Methods: Retrospective study of neonates born between January 2003 and Deccember 2018, who underwent ductus arteriosus closure by p...

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Published in:Revista Paulista de Pediatria 2021-01, Vol.39
Main Authors: Faim, Diogo Remi Oliveira, Tiago, Joaquim António Maia, Castelo, Rui Jorge Simões, Francisco, Andreia Sofia Santos, Alves, Rosa Ramalho, Pires, António Manuel Guerra Santos
Format: Article
Language:English
Subjects:
Acetaminophen
Ductus arteriosus, patent
Ibuprofen
Infant, premature
Neonatology
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Summary:ABSTRACT Objective: To characterize the number and methods of closure of Persistent Ductus Arteriosus (PDA) over a span of 16 years in a third level maternity hospital. Methods: Retrospective study of neonates born between January 2003 and Deccember 2018, who underwent ductus arteriosus closure by pharmacological, surgical and/or transcatheter methods. Gestational age, birth weight, number and methods of closures per year were evaluated. The success rate of the pharmacologic method was calculated, as well as the mortality rate. The association between mortality and birthweight, treatment used and treatment failure was explored. Results: There were 47,198 births, 5,156 were preterm, 325 presented PDA and 106 were eligible for closure (median gestational age - 27 weeks, birthweight
ISSN:0103-0582
1984-0462
DOI:10.1590/1984-0462/2021/39/2020013