Sleep and immune function among people living with human immunodeficiency virus (HIV)

People living with HIV are at increased risk for sleep disturbances. Up to 75% of the HIV-infected individuals in the United States experience sleep disturbances of some kind. Previous studies have suggested an association between patient-reported sleep disturbances and impaired immune function. Thi...

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Bibliographic Details
Published in:AIDS care 2021-09, Vol.33 (9), p.1196-1200
Main Authors: Balthazar, Monique S., Webel, Allison, Gary, Faye, Burant, Christopher J., Totten, Vicken Y., Voss, Joachim G.
Format: Article
Language:English
Subjects:
Actigraphy
CD4 antigen
CD4+ T- lymphocyte count
Cell number
Disturbances
Evaluation
HIV
Human immunodeficiency virus
Immune response
Immune system
Lymphocytes
Sleep
Sleep disorders
viral load
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Summary:People living with HIV are at increased risk for sleep disturbances. Up to 75% of the HIV-infected individuals in the United States experience sleep disturbances of some kind. Previous studies have suggested an association between patient-reported sleep disturbances and impaired immune function. This study evaluates data obtained via sleep actigraphy to evaluate the relationship between objectively measured sleep, HIV viral load, and immune function. While this study found no relationship between objective sleep and CD4+ T- lymphocyte count, higher sleep efficiency was weakly correlated with lower HIV viral loads, τ b (93)   = −.165, p = .043. More research is warranted to clarify the nature of these relationships.
ISSN:0954-0121
1360-0451
DOI:10.1080/09540121.2020.1770180