Visual Loss after Platelet-rich Plasma Injection into the Face

Platelet-rich plasma has become one of the most widely used facial cosmetics fillers. We evaluated four patients treated by cosmetologists with platelet-rich plasma injections who developed irreversible blindness due to iatrogenic occlusion of the ophthalmic artery; immediately after the injection i...

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Published in:Neuro-ophthalmology (Amsterdam : Aeolus Press. 1980) 2020-11, Vol.44 (6), p.371-378
Main Authors: Karam, Emely Z, Gan, Alexander, Muci Mendoza, Rafael, Martinez, Edwing, Perez, Evlyn
Format: Article
Language:English
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Summary:Platelet-rich plasma has become one of the most widely used facial cosmetics fillers. We evaluated four patients treated by cosmetologists with platelet-rich plasma injections who developed irreversible blindness due to iatrogenic occlusion of the ophthalmic artery; immediately after the injection in the glabellar area in three cases and in the nasolabial fold in one case. Early after the injections the fundi of all patients demonstrated central retinal artery and choroidal occlusions. Later, two patients developed retinal pigment dispersion and one of them a pigmented optic disc. The scars on the skin showed similar characteristics in all patients, which could constitute an important marker in the presumptive diagnosis of platelet-rich plasma injection associated complications.
ISSN:0165-8107
1744-506X
DOI:10.1080/01658107.2020.1740936