From an asymptomatic lesion to a vision-threatening condition: Congenital hypertrophy of the retinal pigment epithelium complicated by choroidal neovascular membrane

We reported a case of congenital hypertrophy of the retinal pigment epithelium (CHRPE) complicated by choroidal neovascular membrane (CNVM). A 41-year-old woman presented to our clinic with visual loss in the left eye. She was diagnosed as CHRPE complicated by a CNVM. The patient was treated with 2...

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Bibliographic Details
Published in:Indian journal of ophthalmology 2020-10, Vol.68 (10), p.2288-2290
Main Authors: Gün, Raziye, Akcay, Güzide, Kanar, Hatice, Şimşek, Şaban
Format: Article
Language:English
Subjects:
Acuity
Adult
Angiogenesis Inhibitors - therapeutic use
Care and treatment
Case Reports
Case studies
Choroidal Neovascularization - diagnosis
Choroidal Neovascularization - drug therapy
Choroidal Neovascularization - etiology
Diagnosis
Epithelium
Female
Genetic disorders
Humans
Hypertrophy
Intravitreal Injections
Retina
Retinal diseases
Retinal Pigment Epithelium
Tomography, Optical Coherence
Visual Acuity
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Summary:We reported a case of congenital hypertrophy of the retinal pigment epithelium (CHRPE) complicated by choroidal neovascular membrane (CNVM). A 41-year-old woman presented to our clinic with visual loss in the left eye. She was diagnosed as CHRPE complicated by a CNVM. The patient was treated with 2 consecutive monthly intravitreal aflibercept (IVA) injections. The best-corrected visual acuity (BCVA) improved and stabilized at 6/6. Subretinal fluid depending on CNVM resolved completely. CHRPE complicated by CNVM in the macular area is a rare condition and these cases can be treated with IVA therapy.
ISSN:0301-4738
1998-3689
DOI:10.4103/ijo.IJO_2185_19