Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone

Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural d...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2020, Vol.2020 (2020), p.1-11
Main Authors: Yan, Tingdong, Liu, Zhaoguo, Cai, Yi, He, Yang, Li, Hongshui, Rafiq, Muhammad, Hassan, Sabba, Deng, Zirong, Kang, Xi
Format: Article
Language:English
Subjects:
Analgesics
Antioxidants
Antitumor activity
Apoptosis
Cancer
Cell cycle
Cell growth
Flavonoids
Inflammation
Kinases
Lipid peroxidation
Medicinal plants
Neuroprotection
Oxidative stress
Pain perception
Review
Skin
Tumorigenesis
Tumors
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Summary:Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural drug source to maintain higher health standards due to its excellent therapeutic roles in neuroprotection, cardioprotective activity, hepatoprotective activity, antidiabetes and obesity, and skin protection and having highly analgesic, antioxidant, and anti-inflammatory effects, antipyretic and antinociceptive actions, antitumor activity, and much more. This review aims to highlight the modes of action of eriodictyol against various diseases via multiple cellular signaling pathways.
ISSN:1741-427X
1741-4288
DOI:10.1155/2020/6681352